Next-generation sequencing: big data meets high performance computing

B Schmidt, A Hildebrandt - Drug discovery today, 2017 - Elsevier
Highlights•Analysis of massive NGS datasets poses difficult computational challenges.•Big
data algorithms are often adapted for NGS analysis.•HPC becomes pivotal as NGS …

Enabling fast and energy-efficient FM-index exact matching using processing-near-memory

JM Herruzo, I Fernandez, S González-Navarro… - The Journal of …, 2021 - Springer
Memory bandwidth and latency constitutes a major performance bottleneck for many data-
intensive applications. While high-locality access patterns take advantage of the deep cache …

An effective and fast soccer ball detection and tracking method

XF Tong, HQ Lu, QS Liu - Proceedings of the 17th International …, 2004 - ieeexplore.ieee.org
A ball detection and tracking approach in real soccer game is proposed in this paper. In view
of difficulties of direct detection, an indirect strategy based on non-ball elimination is applied …

Emerging Trends of Big Data in Bioinformatics and Challenges

A Sharma, T Pal, U Naithani, G Gupta… - … Data Analytics for …, 2024 - Wiley Online Library
Current technologies are much more advanced, and they greatly outpace storage,
organizing, analyzing, and extracting capabilities. The rapid and cost‐effective generation of …

ViraPipe: scalable parallel pipeline for viral metagenome analysis from next generation sequencing reads

AI Maarala, Z Bzhalava, J Dillner, K Heljanko… - …, 2018 - academic.oup.com
Abstract Motivation Next Generation Sequencing (NGS) technology enables identification of
microbial genomes from massive amount of human microbiomes more rapidly and cheaper …

Accelerating sequence alignments based on FM-index using the Intel KNL processor

JM Herruzo, S González-Navarro… - … ACM transactions on …, 2018 - ieeexplore.ieee.org
FM-index is a compact data structure suitable for fast matches of short reads to large
reference genomes. The matching algorithm using this index exhibits irregular memory …

Novel computational techniques for mapping and classification of Next-Generation Sequencing data

K Brinda - 2016 - hal.science
Since their emergence around 2006, Next-Generation Sequencing technologies have been
revolutionizing biological and medical research. Obtaining instantly an extensive amount of …

Compressed sparse FM-index: Fast sequence alignment using large k-steps

R Langarita, A Armejach, J Setoain… - IEEE/ACM …, 2020 - ieeexplore.ieee.org
The FM-index is a data structure used in genomics for exact search of input sequences over
large reference genomes. Algorithms based on the FM-index show an irregular memory …

S-Aligner: Ultrascalable read mapping on sunway taihu light

X Duan, K Xu, Y Chan, C Hundt… - 2017 IEEE …, 2017 - ieeexplore.ieee.org
The availability and amount of sequenced genomes have been rapidly growing in recent
years because of the adoption of next-generation sequencing (NGS) technologies that …

[图书][B] Scalable parallel algorithms for genome analysis

E Georganas - 2016 - search.proquest.com
A critical problem for computational genomics is the problem of de novo genome assembly:
the development of robust scalable methods for transforming short randomly sampled …