Progresses over the past years have extensively improved our capacity to use genome-
scale analyses—including high-density genotyping and exome and genome sequencing …

Oxaliplatin is the first-line regime for advanced gastric cancer treatment, while its resistance
is a major problem that leads to the failure of clinical treatments. Tumor cell heterogeneity …

Neuroblastoma is a very diverse pediatric tumor that starts from the neural crest, and it is
responsible over more than 15% of all juvenile cancer deaths. Clinical signs and symptoms …

Neuroblastoma (NB) is the most common extracranial tumor in children. YTHDC1, a member
of RNA methylation modification binding proteins, plays critical roles in tumor occurrence …

High-Risk neuroblastoma (NB) survival rate is still< 50%, despite treatments being more and
more aggressive. The biggest hurdle liable to cancer therapy failure is the drug resistance …

Background Emerging evidence suggests that non-coding somatic single nucleotide
variants (SNVs) in cis-regulatory elements (CREs) contribute to cancer by disrupting gene …

Therapeutic resistance is one of the significant challenges in Neuroblastoma. Owing to its
molecular diversity, the therapeutic resistance mechanisms of Neuroblastoma are highly …

Neuroblastoma is a primary malignancy mainly occurring in children. We have reported that
polymorphisms of several N6-methyladenosine (m6A) RNA modification-related genes …

Neuroblastoma (NB) is the most common type of extracranial solid tumor found in children.
Despite several treatment options, patients with advanced stage disease have a poor …

Discoveries in the field of genomics have revealed that non-coding genomic regions are not
merely" junk DNA", but rather comprise critical elements involved in gene expression. These …