Despite decades of suppressive antiretroviral therapy, human immunodeficiency virus (HIV)
reservoirs in infected individuals persist and fuel viral rebound once therapy is interrupted …

Understanding the drivers and markers of clonally expanding HIV-1-infected CD4+ T cells is
essential for HIV-1 eradication. We used single-cell ECCITE-seq, which captures surface …

Despite long-term antiretroviral therapy (ART), HIV-1 persists within a reservoir of CD4+ T
cells that contribute to viral rebound if treatment is interrupted. Identifying the cellular …

More than 50% of the HIV-1 latent reservoir is maintained by clonal expansion. The clonally
expanded HIV-1-infected cells can contribute to persistent nonsuppressible low-level …

Persistence of HIV in people living with HIV (PWH) on suppressive antiretroviral therapy
(ART) has been linked to physiological mechanisms of CD4+ T cells. Here, in the same 37 …

HIV-1 persists indefinitely in people living with HIV (PLWH) on antiretroviral therapy (ART). If
ART is stopped, the virus rapidly rebounds from long-lived latently infected cells. Using a …

Clinical outcomes are inferior for individuals with HIV having suboptimal CD4 T-cell recovery
during antiretroviral therapy (ART). We investigated if the levels of infection and the …

Historically, naive cells have been considered inconsequential to HIV persistence. Here, we
compared the contributions of naive and memory cells to the reservoirs of individuals with a …

The use of antiretroviral therapy (ART) for Human Immunodeficiency Virus (HIV) treatment
has been highly successful in controlling plasma viremia to undetectable levels. However, a …

Human immunodeficiency virus (HIV) infection remains an important global public health
problem. About 40 million people are infected with HIV, and this infection caused about …