A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Despite significant therapeutic advances, the prognosis of patients with heart failure (HF)
remains poor, and current therapeutic approaches are palliative in the sense that they do not …

Ischemic heart disease is the leading cause of death worldwide. Myocardial infarction
results in an irreversible loss of cardiomyocytes with subsequent adverse remodeling and …

Mesenchymal stem cells (MSCs) are defined as cells that undergo sustained in vitro growth
and can give rise to multiple mesenchymal lineages. Because MSCs have only been …

Cardiac regeneration is a rapidly evolving and controversial field of research. The
identification some 12 years ago of progenitor cells that reside within the heart spurred …

Multipotent mesenchymal stromal/stem cells (MSCs) reside in many human organs and
comprise heterogeneous population of cells with self‐renewal ability. These cells can be …

Multipotent adult resident cardiac stem cells (CSCs) were first identified by the expression of
c-kit, the stem cell factor receptor. However, in the adult myocardium c-kit alone cannot …

The beneficial effects of oxytocin on infarct size and functional recovery of the ischemic
reperfused heart are well documented. The mechanisms for this cardioprotection are not …

Stem cells have the potential to differentiate into cardiovascular cell lineages and to
stimulate tissue regeneration in a paracrine/autocrine manner; thus, they have been …

Traditionally associated with female reproduction, oxytocin (OT) was revisited recently and
was revealed to have several new roles in the cardiovascular system. Functional OT …