In spite of the immense advancement in the diagnostic and treatment modalities, cancer
continues to be one of the leading causes of mortality across the globe, responsible for the …

Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …

Piperlongumine (PL), an alkaloid found primarily in the fruits and roots of the plant Piper
longum L.(Piperaceae), is a natural compound that exhibits potent activity against various …

Triple‐negative breast cancer (TNBC) is caused due to the lack of estrogen receptors (ER),
progesterone receptors (PR), and human epidermal growth factor 2 (HER2) expression …

Breast cancer is the second leading cause of death among women, and the number of
mortal cases in diagnosed patients is constantly increasing. The search for new plant …

NF-κB is the principle transcription factor and plays the central role in orchestrating chronic
inflammation by regulating levels of cytokines, chemokines and growth factors …

Triple-negative breast cancer (TNBC) exhibits a proclivity for early recurrence and
development of metastasis. Moreover, drug resistance tends to arise few months following …

Ocular retinoblastoma malignancies, which develop into metastatic phenotypes, result in
poor prognosis and survival for infant and child patients. To improve the prognosis of …

Cancer is a worldwide health problem with high mortality in children and adults, making
searching for novel bioactive compounds with potential use in cancer treatment essential …

Cancer remains one of the leading causes of death worldwide. Various environmental and
lifestyle factors that can be modified are linked to the development of different cancers …