Fiber photometry is a key technique for characterizing brain-behavior relationships in vivo.
Initially, it was primarily used to report calcium dynamics as a proxy for neural activity via …

The neuromodulator dopamine (DA) is essential for regulating learning, motivation, and
movement. Despite its importance, however, the mechanisms by which DA influences the …

With rapid aging of the population worldwide, the number of people with dementia is
dramatically increasing. Some studies have emphasized that metabolic syndrome, which …

Neuropeptides have important roles in neural plasticity, spiking and behaviour. Yet, many
fundamental questions remain regarding their spatiotemporal transmission, integration and …

Liraglutide and other glucagon-like peptide 1 receptor agonists (GLP-1RAs) are effective
weight loss drugs, but how they suppress appetite remains unclear. One potential …

Neural circuits and the cells that comprise them represent the functional units of the brain.
Circuits relay and process sensory information, maintain homeostasis, drive behaviors, and …

To make adaptive decisions, we build an internal model of the associative relationships in
an environment and use it to make predictions and inferences about specific available …

Midbrain dopaminergic neurons are a relatively small group of neurons in the mammalian
brain controlling a wide range of behaviors. In recent years, increasingly sophisticated …

Retinal ganglion cell (RGC) types relay parallel streams of visual feature information. We
hypothesized that neuromodulators might efficiently control which visual information streams …

We investigated how transmission of hunger-and satiety-promoting neuropeptides, NPY and
αMSH, is integrated at the level of intracellular signaling to control feeding. Receptors for …