Natural product interventions for chemotherapy and radiotherapy-induced side effects

QY Zhang, FX Wang, KK Jia, LD Kong - Frontiers in pharmacology, 2018 - frontiersin.org
Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy
are the common cancer treatments. However, the development of adverse effects resulting …

Combating oxidative stress disorders with citrus flavonoid: Naringenin

NH Zaidun, ZC Thent, A Abd Latiff - Life sciences, 2018 - Elsevier
The incidence of diseases related to oxidative stress disorders have been increased
dramatically. Alternatives medicine or the active compound extracted from the natural …

Multi-therapeutic potential of naringenin (4′, 5, 7-trihydroxyflavonone): experimental evidence and mechanisms

A Arafah, MU Rehman, TM Mir, AF Wali, R Ali… - Plants, 2020 - mdpi.com
Extensive research has been carried out during the last few decades, providing a detailed
account of thousands of discovered phytochemicals and their biological activities that have …

Prussian blue nanozymes prevent anthracycline-induced liver injury by attenuating oxidative stress and regulating inflammation

H Bai, F Kong, K Feng, X Zhang, H Dong… - … applied materials & …, 2021 - ACS Publications
Anthracycline-induced liver injury (AILI) is becoming an increasingly serious and potential
clinical complication and is linked to reactive oxygen species (ROS) production and …

Collaborative Power of Nrf2 and PPARγ Activators against Metabolic and Drug‐Induced Oxidative Injury

C Lee - Oxidative medicine and cellular longevity, 2017 - Wiley Online Library
Mammalian cells have evolved a unique strategy to protect themselves against oxidative
damage induced by reactive oxygen species (ROS). Especially, two transcription factors …

A recent review of citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production

N Karim, Z Jia, X Zheng, S Cui, W Chen - Trends in Food Science & …, 2018 - Elsevier
Background Metabolic syndromes are the multi-metabolic abnormality characterized by
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …

Naringenin regulates doxorubicin-induced liver dysfunction: impact on oxidative stress and inflammation

AF Wali, S Rashid, SM Rashid, MA Ansari, MR Khan… - Plants, 2020 - mdpi.com
Doxorubicin (Dox) is an operational and largely used anticancer drug, used to treat an array
of malignancies. Nonetheless, its beneficial use is constrained due to its renal and …

Biological activities of naringenin: A narrative review based on in vitro and in vivo studies

K Uçar, Z Göktaş - Nutrition Research, 2023 - Elsevier
Abstract Naringenin (4′, 5, 7-trihydroxyflavonone) is a phytochemical that is mainly found in
citrus fruits. It is a promising phytochemical for human health due to its beneficial effects …

Flavonoids, the compounds with anti-inflammatory and immunomodulatory properties, as promising tools in multiple sclerosis (MS) therapy: a systematic review of …

P Bayat, M Farshchi, M Yousefian, M Mahmoudi… - International …, 2021 - Elsevier
Multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE), an animal
model of MS, are diseases resulting in neurological disabilities that are regarded as chronic …

Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling …

MF Manchope, C Calixto-Campos, L Coelho-Silva… - PloS one, 2016 - journals.plos.org
In the present study, the effect and mechanism of action of the flavonoid naringenin were
evaluated in superoxide anion donor (KO2)-induced inflammatory pain in mice. Naringenin …