All-trans retinoic acid in hematologic disorders: not just acute promyelocytic leukemia
Y Chen, X Tong, R Lu, Z Zhang, T Ma - Frontiers in Pharmacology, 2024 - frontiersin.org
All-trans retinoic acid (ATRA) plays a role in tissue development, neural function,
reproduction, vision, cell growth and differentiation, tumor immunity, and apoptosis. ATRA …
reproduction, vision, cell growth and differentiation, tumor immunity, and apoptosis. ATRA …
Metabolic reprogramming driven by IGF2BP3 promotes acquired resistance to EGFR inhibitors in non–small cell lung cancer
Z Lin, J Li, J Zhang, W Feng, J Lu, X Ma, W Ding… - Cancer …, 2023 - aacrjournals.org
Acquired resistance represents a bottleneck for effective molecular targeted therapy in lung
cancer. Metabolic adaptation is a distinct hallmark of human lung cancer that might …
cancer. Metabolic adaptation is a distinct hallmark of human lung cancer that might …
Platelets in ITP: victims in charge of their own fate?
VS Nelson, ATC Jolink, SN Amini, JJ Zwaginga… - Cells, 2021 - mdpi.com
Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder. The
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …
pathophysiological mechanisms leading to low platelet levels in ITP have not been resolved …
[HTML][HTML] RNA binding protein IGF2BP1 meditates oxidative stress-induced granulosa cell dysfunction by regulating MDM2 mRNA stability in an m6A-dependent …
H Mu, S Cai, X Wang, H Li, L Zhang, H Li, W Xiang - Redox biology, 2022 - Elsevier
Both genetic and microenvironmental detrimental factors are involved in ovarian
dysfunction, leading to the increasing rate of involuntary childlessness in recent years …
dysfunction, leading to the increasing rate of involuntary childlessness in recent years …
Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells
L Ma, L Zhang, Y Zhuang, Y Ding, J Chen - Cell Communication and …, 2022 - Springer
Background Autoimmune hepatitis (AIH) is a chronic, immune-mediated liver dysfunction.
The gut microbiota and T follicular helper (Tfh) cells play critical roles in the …
The gut microbiota and T follicular helper (Tfh) cells play critical roles in the …
Therapeutic potential of MSCs and MSC-derived extracellular vesicles in immune thrombocytopenia
F Wu, Z She, C Li, J Mao, S Luo, X Chen, J Tian… - Stem Cell Research & …, 2023 - Springer
Immune thrombocytopenia (ITP) is an acquired autoimmune disease involving a variety of
immune cells and factors. Despite being a benign disease, it is still considered incurable …
immune cells and factors. Despite being a benign disease, it is still considered incurable …
Autoimmune effector mechanisms associated with a defective immunosuppressive axis in immune thrombocytopenia (ITP)
Q Li, G Marcoux, Y Hu, J Rebetz, L Guo, E Semple… - Autoimmunity …, 2024 - Elsevier
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by an isolated
thrombocytopenia and variable phenotype as some patients suffer no bleeding whilst others …
thrombocytopenia and variable phenotype as some patients suffer no bleeding whilst others …
miR-4721, induced by EBV-miR-BART22, targets GSK3β to enhance the tumorigenic capacity of NPC through the WNT/β-catenin pathway
ZB Tang, WF Chen, Y Xu, X Lin, X Liu, YH Li… - … Therapy-Nucleic Acids, 2020 - cell.com
Nasopharyngeal carcinoma (NPC) is prevalent in East and Southeast Asia. In a previous
study, Epstein-Barr virus (EBV)-miR-BART22 induces tumor metastasis and stemness and is …
study, Epstein-Barr virus (EBV)-miR-BART22 induces tumor metastasis and stemness and is …
The role of insulin-like growth factor 2 mRNA binding proteins in female reproductive pathophysiology
X Xu, HR Shen, JR Zhang, XL Li - Reproductive Biology and …, 2022 - Springer
Insulin-like growth factor 2 (IGF2) mRNA binding proteins (IMPs) family belongs to a highly
conserved family of RNA-binding proteins (RBPs) and is responsible for regulating RNA …
conserved family of RNA-binding proteins (RBPs) and is responsible for regulating RNA …
Bone marrow mesenchymal stem cell-derived exosomes induce the Th17/Treg imbalance in immune thrombocytopenia through miR-146a-5p/IRAK1 axis
Y He, D Ji, W Lu, F Li, X Huang, R Huang, G Chen - Human Cell, 2021 - Springer
Bone marrow mesenchymal stem cells (BMSCs) are associated with immune
thrombocytopenia (ITP), the underlying mechanism has not been fully elucidated. Here, we …
thrombocytopenia (ITP), the underlying mechanism has not been fully elucidated. Here, we …