Recent progress in aptamer discoveries and modifications for therapeutic applications

S Ni, Z Zhuo, Y Pan, Y Yu, F Li, J Liu… - … Applied Materials & …, 2020 - ACS Publications
Aptamers are oligonucleotide sequences with a length of about 25–80 bases which have
abilities to bind to specific target molecules that rival those of monoclonal antibodies. They …

Functional supramolecular systems: Design and applications

IS Antipin, MV Alfimov, VV Arslanov… - Russian Chemical …, 2021 - iopscience.iop.org
The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

[HTML][HTML] Current perspectives on aptamers as diagnostic tools and therapeutic agents

P Kumar Kulabhusan, B Hussain, M Yüce - Pharmaceutics, 2020 - mdpi.com
Aptamers are synthetic single-stranded DNA or RNA sequences selected from combinatorial
oligonucleotide libraries through the well-known in vitro selection and iteration process …

Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Design and development of graphene oxide nanoparticle/chitosan hybrids showing pH-sensitive surface charge-reversible ability for efficient intracellular doxorubicin …

X Zhao, Z Wei, Z Zhao, Y Miao, Y Qiu… - … applied materials & …, 2018 - ACS Publications
A novel graphene oxide nanoparticle (GON)-based drug delivery system containing GONs
as carriers of anticancer drugs and chitosan/dimethylmaleic anhydride-modified chitosan …

Aptamers as versatile ligands for biomedical and pharmaceutical applications

B Guan, X Zhang - International journal of nanomedicine, 2020 - Taylor & Francis
Aptamers are a class of targeting ligands that bind exclusively to biomarkers of interest.
Aptamers have been identified as candidates for the construction of various smart systems …

Aptamers as diagnostic tools in cancer

D Ruiz Ciancio, MR Vargas, WH Thiel, MA Bruno… - Pharmaceuticals, 2018 - mdpi.com
Cancer is the second leading cause of death worldwide. Researchers have been working
hard on investigating not only improved therapeutics but also on early detection methods …

A facile surface modification strategy for fabrication of fluorescent silica nanoparticles with the aggregation-induced emission dye through surface-initiated cationic ring …

L Huang, S Yang, J Chen, J Tian, Q Huang… - Materials Science and …, 2019 - Elsevier
Fluorescent silica nanoparticles (FSNPs) have attracted great interest for potential
applications in biological and biomedical fields because they possess higher fluorescence …

Optical assays based on colloidal inorganic nanoparticles

A Ghasemi, N Rabiee, S Ahmadi, S Hashemzadeh… - Analyst, 2018 - pubs.rsc.org
Colloidal inorganic nanoparticles have wide applications in the detection of analytes and in
biological assays. A large number of these assays rely on the ability of gold nanoparticles …

Therapeutic Potential of Aptamer–Protein Interactions

AS Shraim, BA Abdel Majeed… - ACS Pharmacology & …, 2022 - ACS Publications
Aptamers are single-stranded oligonucleotides (RNA or DNA) with a typical length between
25 and 100 nucleotides which fold into three-dimensional structures capable of binding to …