Riboregulation in bacteria: From general principles to novel mechanisms of the trp attenuator and its sRNA and peptide products

E Evguenieva‐Hackenberg - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Gene expression strategies ensuring bacterial survival and competitiveness rely on cis‐and
trans‐acting RNA‐regulators (riboregulators). Among the cis‐acting riboregulators are …

Sequence specificity in DNA binding is mainly governed by association

E Marklund, G Mao, J Yuan, S Zikrin… - Science, 2022 - science.org
Sequence-specific binding of proteins to DNA is essential for accessing genetic information.
We derive a model that predicts an anticorrelation between the macroscopic association and …

Small RNAs and Hfq capture unfolded RNA target sites during transcription

ML Rodgers, B O'Brien, SA Woodson - Molecular cell, 2023 - cell.com
Small ribonucleoproteins (sRNPs) target nascent precursor RNAs to guide folding,
modification, and splicing during transcription. Yet, rapid co-transcriptional folding of the …

Detachable DNA assembly module to dissect tumor cells heterogeneity via RNA pinpoint screening

W Liu, N Liao, Y Lei, W Liang, X Yang… - Advanced …, 2024 - Wiley Online Library
Differential RNA expression is becoming increasingly valuable in evaluating tumor
heterogeneity for a better understanding of malignant tumors and guiding personalized …

The 3′UTR‐derived sRNA RsaG coordinates redox homeostasis and metabolism adaptation in response to glucose‐6‐phosphate uptake in Staphylococcus aureus

E Desgranges, L Barrientos, L Herrgott… - Molecular …, 2022 - Wiley Online Library
Staphylococcus aureus RsaG is a 3′‐untranslated region (3′ UTR) derived sRNA from
the conserved uhpT gene encoding a glucose‐6‐phosphate (G6P) transporter expressed in …

G6P-capturing molecules in the periplasm of Escherichia coli accelerate the shikimate pathway

R Fujiwara, M Nakano, Y Hirata, C Otomo… - Metabolic …, 2022 - Elsevier
Escherichia coli, the most studied prokaryote, is an excellent host for producing valuable
chemicals from renewable resources as it is easy to manipulate genetically. Since the …

Bacterial Small RNAs: Diversity of Structure and Function

JP Sousa, AFQ Silva, CM Arraiano… - RNA Structure and …, 2023 - Springer
Small non-coding RNAs (sRNAs) are key post-transcriptional regulators of gene expression
in bacteria, with a diversity of origins, sequences, structures, and modes of action among …

[HTML][HTML] Gene knockdown by structure defined single-stem loop small non-coding RNAs with programmable regulatory activities

Y Wang, G Yin, H Weng, L Zhang, G Du, J Chen… - Synthetic and Systems …, 2023 - Elsevier
Gene regulation by trans-acting small RNAs (sRNAs) has considerable advantages over
other gene regulation strategies. However, synthetic sRNAs mainly take natural sRNAs …