Genomics-based precision medicine has revolutionized oncology but also has inherent
limitations. Functional precision oncology is emerging as a complementary approach that …

BACKGROUND To provide the optimal milieu for implantation and fetal development, the
female reproductive system must orchestrate uterine dynamics with the appropriate …

Predicting the clinical response to chemotherapeutic or targeted treatment in patients with
locally advanced or metastatic lung cancer requires an accurate and affordable tool. Tumor …

Basic and clinical cancer research requires tumor models that consistently recapitulate the
characteristics of prima tumors. As ex vivo 3D cultures of patient tumor cells, patient‐derived …

Organoids are a class of multicellular structures with the capability of self-organizing and the
characteristic of original tissues, they are generated from stem cells in 3D culture in vitro …

Background High grade serous ovarian cancer (HGSOC) is among the deadliest human
cancers and its prognosis remains extremely poor. Tumor heterogeneity and rapid …

Personalized treatment for patients with advanced solid tumors critically depends on the
deep characterization of tumor cells from patient biopsies. Here, we comprehensively …

High-grade serous ovarian cancer (HGSOC) is the most frequent and aggressive type of
epithelial ovarian cancer, with high recurrence rate and chemoresistance being the main …

Head and neck cancers (HNC) are the seventh most prevalent cancer type globally. Despite
their common categorisation, HNCs are a heterogeneous group of malignancies arising in …

Simple Summary In the conventional treatment of gynecologic malignancies, most patients
receive similar 'one-size-fits-all'treatment. However, it is increasingly clear that standard …