[HTML][HTML] USP6 activation in nodular fasciitis by promoter-swapping gene fusions

NR Patel, JSA Chrisinger, EG Demicco, SF Sarabia… - Modern pathology, 2017 - Elsevier
Nodular fasciitis is a self-limited myofibroblastic lesion that can be misdiagnosed as a
sarcoma as a result of its rapid growth, cellularity, and sometimes prominent mitotic activity …

MicroRNA-21 in cancer-associated fibroblasts supports lung adenocarcinoma progression

A Kunita, S Morita, TU Irisa, A Goto, T Niki, D Takai… - Scientific reports, 2018 - nature.com
Cancer-associated fibroblasts (CAFs) interact closely with cancer cells, supporting their
growth and invasion. To investigate the role of microRNA-21 (miR-21) in lung …

What is the role of PIWI family proteins in adult pluripotent stem cells? Insights from asexually reproducing animals, planarians

M Kashima, K Agata, N Shibata - Development, Growth & …, 2020 - Wiley Online Library
Planarians have a remarkable regenerative ability owing to their adult pluripotent stem cells
(aPSCs), which are called “neoblasts.” Planarians maintain a considerable number of …

Five EMT‐related genes signature predicts overall survival and immune environment in microsatellite instability‐high gastric cancer

M Zhang, C Cao, X Li, Q Gu, Y Xu, Z Zhu, D Xu… - Cancer …, 2023 - Wiley Online Library
Background Microsatellite instability‐high (MSI‐H) subgroup of gastric cancer (GC) is
characterized by a high tumor mutational burden, increased lymphocytic infiltration, and …

CALU promotes lung adenocarcinoma progression by enhancing cell proliferation, migration and invasion

Y Li, S Sun, H Zhang, Y Jing, X Ji, Q Wan, Y Liu - Respiratory Research, 2024 - Springer
Background Lung cancer is the second most common cancer with the highest mortality in
the world. Calumenin as a molecular chaperone that not only binds various proteins within …

Structural Plasticity Allows Calumenin-1 to Moonlight as a Ca2+-Independent Chaperone: Pb2+ Enables Probing Alternate Inhibitory Conformation

MP Yadav, S Narayanasamy, GK Aradhyam - Biochemistry, 2023 - ACS Publications
Human calumenin-1 (HsCalu-1) is an endoplasmic reticulum (ER) and Golgi-resident Ca2+-
binding protein of the hepta-EF-hand superfamily that plays a vital role in maintaining the …

Establishment of a CALU, AURKA, and MCM2 gene panel for discrimination of metastasis from primary colon and lung cancers

P Nasri Nasrabadi, Z Nayeri, E Gharib, R Salmanipour… - Plos one, 2020 - journals.plos.org
Metastasis is known as a key step in cancer recurrence and could be stimulated by multiple
factors. Calumenin (CALU) is one of these factors which has a direct impact on cancer …

Development of a zinc (ii) 2-pyridinecarboxaldehyde thiosemicarbazone complex with remarkable antitumor and antiangiogenic activities

M Jiang, J Pang, X Jia, Y Chu, W Li, H Liang… - Dalton …, 2023 - pubs.rsc.org
To develop the next-generation metal agents for efficiently inhibiting tumor growth, we
synthesized a series of new Zn (II) complexes (C1–C5) derived from 2 …

[HTML][HTML] Prostate stromal cell proteomics analysis discriminates normal from tumour reactive stromal phenotypes

JP Webber, LK Spary, MD Mason, Z Tabi, IA Brewis… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Changes within interstitial stromal compartments often accompany carcinogenesis,
and this is true of prostate cancer. Typically, the tissue becomes populated by myofibroblasts …

Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors

J Hou, S Liang, C Xu, Y Wei, Y Wang, Y Tan… - NAR …, 2022 - academic.oup.com
Genetic screens are widely exploited to develop novel therapeutic approaches for cancer
treatment. With recent advances in single-cell technology, single-cell CRISPR screen …