The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota
C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …
Mouse models for human intestinal microbiota research: a critical evaluation
F Hugenholtz, WM de Vos - Cellular and Molecular Life Sciences, 2018 - Springer
Since the early days of the intestinal microbiota research, mouse models have been used
frequently to study the interaction of microbes with their host. However, to translate the …
frequently to study the interaction of microbes with their host. However, to translate the …
Host genetics influence the rumen microbiota and heritable rumen microbial features associate with feed efficiency in cattle
Background The symbiotic rumen microbiota is essential for the digestion of plant fibers and
contributes to the variation of production and health traits in ruminants. However, to date, the …
contributes to the variation of production and health traits in ruminants. However, to date, the …
The effect of host genetics on the gut microbiome
The gut microbiome is affected by multiple factors, including genetics. In this study, we
assessed the influence of host genetics on microbial species, pathways and gene ontology …
assessed the influence of host genetics on microbial species, pathways and gene ontology …
Genetic determinants of the gut microbiome in UK twins
Studies in mice and humans have revealed intriguing associations between host genetics
and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in …
and the microbiome. Here we report a 16S rRNA-based analysis of the gut microbiome in …
Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease
Objective Patients with IBD display substantial heterogeneity in clinical characteristics. We
hypothesise that individual differences in the complex interaction of the host genome and …
hypothesise that individual differences in the complex interaction of the host genome and …
Host genetic variation impacts microbiome composition across human body sites
R Blekhman, JK Goodrich, K Huang, Q Sun… - Genome biology, 2015 - Springer
Background The composition of bacteria in and on the human body varies widely across
human individuals, and has been associated with multiple health conditions. While microbial …
human individuals, and has been associated with multiple health conditions. While microbial …
Host genetics and the rumen microbiome jointly associate with methane emissions in dairy cows
Cattle and other ruminants produce large quantities of methane (~ 110 million metric tonnes
per annum), which is a potent greenhouse gas affecting global climate change. Methane …
per annum), which is a potent greenhouse gas affecting global climate change. Methane …
Diet shapes the gut microbiome of pigs during nursing and weaning
Background The newborn mammal is rapidly colonized by a complex microbial community,
whose importance for host health is becoming increasingly clear. Understanding the forces …
whose importance for host health is becoming increasingly clear. Understanding the forces …
Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota
Human gut microbiota is an important determinant for health and disease, and recent
studies emphasize the numerous factors shaping its diversity. Here we performed a genome …
studies emphasize the numerous factors shaping its diversity. Here we performed a genome …