New anti-inflammatory targets for chronic obstructive pulmonary disease
PJ Barnes - Nature reviews Drug discovery, 2013 - nature.com
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation of
the peripheral airways and lung parenchyma, which leads to progressive obstruction of the …
the peripheral airways and lung parenchyma, which leads to progressive obstruction of the …
[HTML][HTML] Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic …
Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …
Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice
SM Cloonan, K Glass, ME Laucho-Contreras… - Nature medicine, 2016 - nature.com
Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and
genetic determinants. We have previously identified iron-responsive element–binding …
genetic determinants. We have previously identified iron-responsive element–binding …
Genetics of COPD
EK Silverman - Annual review of physiology, 2020 - annualreviews.org
Although chronic obstructive pulmonary disease (COPD) risk is strongly influenced by
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …
cigarette smoking, genetic factors are also important determinants of COPD. In addition to …
Lessons from ECLIPSE: a review of COPD biomarkers
The Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points
(ECLIPSE) study was a large 3-year observational controlled multicentre international study …
(ECLIPSE) study was a large 3-year observational controlled multicentre international study …
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry
Background Pulmonary function decline is a major contributor to morbidity and mortality
among smokers. Post bronchodilator FEV 1 and FEV 1/FVC ratio are considered the …
among smokers. Post bronchodilator FEV 1 and FEV 1/FVC ratio are considered the …
Genetic advances in chronic obstructive pulmonary disease. Insights from COPDGene
Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that
is influenced by both genetic and environmental factors. For many years, knowledge of the …
is influenced by both genetic and environmental factors. For many years, knowledge of the …
The “iron”-y of iron overload and iron deficiency in chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD) is a debilitating inflammatory lung disease
and the third leading cause of death worldwide (1). COPD is characterized by three major …
and the third leading cause of death worldwide (1). COPD is characterized by three major …
Molecular processes that drive cigarette smoke–induced epithelial cell fate of the lung
T Nyunoya, Y Mebratu, A Contreras… - American journal of …, 2014 - atsjournals.org
Cigarette smoke contains numerous chemical compounds, including abundant reactive
oxygen/nitrogen species and aldehydes, and many other carcinogens. Long-term cigarette …
oxygen/nitrogen species and aldehydes, and many other carcinogens. Long-term cigarette …
Comparison and development of machine learning tools for the prediction of chronic obstructive pulmonary disease in the Chinese population
X Ma, Y Wu, L Zhang, W Yuan, L Yan, S Fan… - Journal of translational …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a major public health
problem and cause of mortality worldwide. However, COPD in the early stage is usually not …
problem and cause of mortality worldwide. However, COPD in the early stage is usually not …