Increasing attention has been focused on understanding bacterial biofilms and this growth
modality's relation to human disease. In this review we explore the genetic regulation and …

Adjuvants incorporated in prophylactic and/or therapeutic vaccine formulations impact
vaccine efficacy by enhancing, modulating, and/or prolonging the immune response. In …

Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

Background A revolutionary diversion from classical vaccinology to reverse vaccinology
approach has been observed in the last decade. The ever-increasing genomic and …

Vaccination is one of the most effective tools for the prevention of infectious diseases. The
availability of complete genome sequences, together with the progression of high …

Vaccines play an essential role in controlling the rates of fatality and morbidity. Vaccines not
only arrest the beginning of different diseases but also assign a gateway for its elimination …

The history of vaccination clearly demonstrates that vaccines have been highly successful in
preventing infectious diseases, reducing significantly the incidence of childhood diseases …

It can be argued that the arrival of the “genomics era” has significantly shifted the paradigm
of vaccine and therapeutics development from microbiological to sequence-based …

Surface proteins play a critical role in the interaction between cells and their environment, as
they take part in processes like signaling, adhesion, transport, etc. In pathogenic …

Vaccine development against pathogenic bacteria is an imperative initiative as bacteria are
gaining resistance to current antimicrobial therapies and few novel antibiotics are being …