An update of anthraquinone derivatives emodin, diacerein, and catenarin in diabetes
M Martorell, N Castro, M Victoriano… - Evidence‐Based …, 2021 - Wiley Online Library
Diabetes is part of metabolic diseases and is characterized by high blood sugar levels over
a prolonged period as result of an insulin‐deficient production or an inappropriate response …
a prolonged period as result of an insulin‐deficient production or an inappropriate response …
How to improve solubility and dissolution of irbesartan by fabricating ternary solid dispersions: optimization and in-vitro characterization
The purpose of this study is to improve the solubility and dissolution of a poorly soluble drug,
Irbesartan, using solid dispersion techniques. For that purpose, different polymers such as …
Irbesartan, using solid dispersion techniques. For that purpose, different polymers such as …
[PDF][PDF] Ibuprofen loaded electrospun polymeric nanofibers: A strategy to improve oral absorption
DS Panda, NK Alruwaili, S Pattnaik… - Acta Chimica …, 2022 - researchgate.net
The poor aqueous solubility of candidate drugs has presented a great challenge to
formulation scientists for their effective oral delivery. Poor solubility is often associated with …
formulation scientists for their effective oral delivery. Poor solubility is often associated with …
Novel inhalable nano-based/microparticles for enhanced sustained pulmonary delivery of remdesivir-A patient malleable treatment for coronaviruses infection: In vitro …
Remdesivir (RDV) is an antiviral used in potential treatment of SARS-COV-2 infection during
the COVID-19 pandemic worldwide. However, it is still limited to IV administration for …
the COVID-19 pandemic worldwide. However, it is still limited to IV administration for …
Enhanced dissolution of sildenafil citrate using solid dispersion with hydrophilic polymers: physicochemical characterization and in vivo sexual behavior studies in …
Sildenafil citrate (SLC) is a frequently used medication (Viagra®) for the treatment of erectile
dysfunction (ED). Due to its poor solubility, SLC suffers from a delayed onset of action and …
dysfunction (ED). Due to its poor solubility, SLC suffers from a delayed onset of action and …
Optimized freeze-dried solid-dispersions boost naringin solubility, antibacterial and in-vitro anticancer activity
SA Alanazi, SS Imam, S Alshehri, MM Alanazi… - Journal of Drug Delivery …, 2024 - Elsevier
Naringin (NRG) is a water insoluble glycoside having wide range of therapeutic efficacy. Its
efficacy is limited due to its poor water solubility and bioavailability. In the current research …
efficacy is limited due to its poor water solubility and bioavailability. In the current research …
Solubility and permeability enhancement of oleanolic acid by solid dispersion in poloxamers and γ-CD
C De Stefani, J Lodovichi, L Albonetti, MC Salvatici… - Molecules, 2022 - mdpi.com
Oleanolic acid (OA) is a pentacyclic triterpenoid widely found in the Oleaceae family, and it
represents 3.5% of the dry weight of olive leaves. OA has many pharmacological activities …
represents 3.5% of the dry weight of olive leaves. OA has many pharmacological activities …
Improved solubility and corneal permeation of PEGylated curcumin complex used for the treatment of ophthalmic bacterial infections
Naturally occurring curcumin can be used for the treatment of corneal bacterial infections
with its limitation of poor solubility. Aim of the present study was to enhance solubility and …
with its limitation of poor solubility. Aim of the present study was to enhance solubility and …
Diacerein loaded novasome for transdermal delivery: Prepartion, in-vitro characterization and factors affecting formulation
NY Albassam, HJ Kassab - … Sciences (P-ISSN 1683-3597 E …, 2023 - bijps.uobaghdad.edu.iq
Diacerein (DCN) is a semi-synthetic anthraquinone derivative of Rhein that is indicated for
the management of osteoarthritis. Diacerein exhibits poor dissolution in the GIT fluids and …
the management of osteoarthritis. Diacerein exhibits poor dissolution in the GIT fluids and …
Assessment of formulation variables of poor water soluble diacerein for its improved loading and anti-inflammatory activity
Dissolving microneedles have become a popular method for percutaneous administrationof
drugs. However, loading poorly soluble drugs into water-based dissolving microneedles …
drugs. However, loading poorly soluble drugs into water-based dissolving microneedles …