Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In
current reproductive medicine, progesterone and its analogues play crucial roles. While the …

While there is not a wide range of pregnancy-specific drugs, there are some very specific
high-risk areas of obstetric care for which unique pharmacological approaches have been …

ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth
ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth …

Background Preterm birth is the leading cause of childhood mortality and morbidity. We
aimed to provide a comprehensive systematic review on randomized controlled trials (RCTs) …

OBJECTIVE Randomized trials have found benefits of both vaginal progesterone and 17-
alpha-hydroxyprogesterone caproate in the prevention of recurrent preterm birth. A previous …

After the FDA pulled 17-hydroxyprogesterone caproate from the market for its use in
prevention of recurrent spontaneous preterm birth, national societies have had mixed …

Objective The frequency of intrahepatic cholestasis of pregnancy (ICP) peaks during the
third trimester of pregnancy when plasma progesterone levels are the highest. Furthermore …

Background Prediction of pregnancies at risk of preterm birth (PTB) may allow targeted
prevention strategies. Objectives To assess quality of clinical practice guidelines (CPGs) …

Background Vaginal progesterone in preterm birth and adverse outcomes caused by
cervical insufficiency remains controversial. To address it, the effect of vaginal progesterone …

2. METHODS The Cochrane rapid review guidance 4 was used to identify systematic
literature reviews (SLRs), randomized controlled trials (RCTs) and observational cohort …