The HOG pathway and the regulation of osmoadaptive responses in yeast

E de Nadal, F Posas - FEMS yeast research, 2022 - academic.oup.com
Cells coordinate intracellular activities in response to changes in the extracellular
environment to maximize their probability of survival and proliferation. Eukaryotic cells need …

[HTML][HTML] Therapeutic potential of ASK1 activators in cancer treatment: Current insights and future directions

B Wang, Y Ma, Y Zhang, X Yin - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Apoptosis signal-regulated kinase 1 (ASK1) is a member of the mitogen-activated protein
kinase kinase (MAP3K) family, whose activation and regulation are intricately associated …

A module centered on the transcription factor Msn2 from arbuscular mycorrhizal fungus Rhizophagus irregularis regulates drought stress tolerance in the host plant

X Fan, H Xie, X Huang, S Zhang, Y Nie… - New …, 2023 - Wiley Online Library
Arbuscular mycorrhizal (AM) fungi can form mutualistic endosymbiosis with> 70% of land
plants for obtaining fatty acids and sugars, in return, AM fungi promote plant nutrients and …

Host‐ and virus‐induced gene silencing of HOG1‐MAPK cascade genes in Rhizophagus irregularis inhibit arbuscule development and reduce resistance of plants to …

S Wang, X Xie, X Che, W Lai, Y Ren… - Plant Biotechnology …, 2023 - Wiley Online Library
Arbuscular mycorrhizal (AM) fungi can form beneficial associations with the most terrestrial
vascular plant species. AM fungi not only facilitate plant nutrient acquisition but also …

Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications

Nitika, B Zheng, L Ruan, JT Kline, S Omkar… - PLoS …, 2022 - journals.plos.org
Hsp70 interactions are critical for cellular viability and the response to stress. Previous
attempts to characterize Hsp70 interactions have been limited by their transient nature and …

The high osmolarity glycerol (HOG) pathway in fungi

H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …

Regulatory mechanisms underlying yeast chemical stress response and development of robust strains for bioproduction

B Yuan, WB Wang, YT Wang, XQ Zhao - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•Chronic stresses related to biotechnology applications are focused.•Epigenetic
regulation benefits dynamic regulation of stress tolerance.•Yeast chemical stress response …

Two activating phosphorylation sites of Pbs2 MAP2K in the yeast HOG pathway are differentially dephosphorylated by four PP2C phosphatases Ptc1–Ptc4

K Tatebayashi, H Saito - Journal of Biological Chemistry, 2023 - ASBMB
To cope with an increased external osmolarity, the budding yeast Saccharomyces
cerevisiae activates the Hog1 mitogen-activated protein kinase (MAPK) through the high …

Herbicide 2,4-dichlorophenoxyacetic acid interferes with MAP kinase signaling in Fusarium graminearum and is inhibitory to fungal growth and pathogenesis

K Duan, Q Shen, Y Wang, P Xiang, Y Shi, C Yang… - Stress Biology, 2023 - Springer
Plant hormones are important for regulating growth, development, and plant-pathogen
interactions. Some of them are inhibitory to growth of fungal pathogens but the underlying …

A walk-through MAPK structure and functionality with the 30-year-old yeast MAPK Slt2

G González-Rubio, Á Sellers-Moya, H Martín… - International …, 2021 - Springer
Mitogen-activated protein kinases (MAPKs) are evolutionarily conserved signaling proteins
involved in the regulation of most eukaryotic cellular processes. They are downstream …