Mechanisms controlling cellular and systemic iron homeostasis

B Galy, M Conrad, M Muckenthaler - Nature Reviews Molecular Cell …, 2024 - nature.com
In mammals, hundreds of proteins use iron in a multitude of cellular functions, including vital
processes such as mitochondrial respiration, gene regulation and DNA synthesis or repair …

[HTML][HTML] Placental ferroportin protein abundance is associated with neonatal erythropoietic activity and iron status in newborns at high risk for iron deficiency and …

A Barad, R Guillet, EK Pressman, PJ Katzman… - The American Journal of …, 2024 - Elsevier
Background Murine data suggest that the placenta downregulates ferroportin (FPN) when
iron is limited to prioritize iron for its own needs. Human data on the impact of maternal and …

Ferrous–sucrose complex supplementation regulates maternal plasma metabolism and the fecal microbiota composition and improves neonatal immunity and …

Z Dong, H Liu, D Wan, X Wu, Y Yin - Food & Function, 2024 - pubs.rsc.org
Pregnancy is a dynamic state involving rapid physiological changes in metabolism, affecting
the health and development of the offspring. During pregnancy, the placenta constitutes a …

Molecular insights into placental iron transfer mechanisms and maternofetal regulation

S Santhakumar, ES Edison - Archives of Gynecology and Obstetrics, 2024 - Springer
Purpose Adequate iron transportation from the mother across the placenta is crucial for fetal
growth and establishing sufficient iron stores in neonates at birth. The past decade has …