Background Targeted temperature management (TTM) is often used in neurocritical care to
minimize secondary neurologic injury and improve outcomes. TTM encompasses …

Neuromuscular blockings agents (NMBAs) have a controversial role in the ventilatory and
medical management of critical illness. The clinical concern surrounding NMBA-induced …

Background The use of processed electroencephalography (pEEG) for depth of sedation
(DOS) monitoring is increasing in anesthesia; however, how to use of this type of monitoring …

Background The absence of the pupillary light reflex (PLR) 3 days after cardiac arrest
predicts poor outcome, but quantitative PLR assessment with pupillometry early after …

Background Outcome prediction after out-of-hospital cardiac arrest (OHCA) may lead to
withdrawal of life-sustaining therapy if the prognosis is perceived negative. Single use of …

Objectives: Sedation and neuromuscular blockade protocols in patients undergoing targeted
temperature management after cardiac arrest address patient discomfort and manage …

Study Objective The free fraction of valproate (the pharmacologically active moiety, normally
5–10%) may vary significantly in critically ill patients, but this topic is understudied, with only …

Neuromuscular blocking agents (NMBA) are a controversial therapeutic option in the
approach to the critically ill patient. They are not innocuous, and the available evidence …

Background An out-of-hospital cardiac arrest (OHCA) with return of spontaneous circulation
(ROSC) may need to be treated with airway management, emergency ventilation, invasive …

Neurocritical care management to improve neurologic outcome for postcardiac arrest
syndrome (PCAS) has focused considerably on targeted temperature management (TTM) …