Biomarkers for the diagnosis and management of heart failure

V Castiglione, A Aimo, G Vergaro, L Saccaro… - Heart failure …, 2022 - Springer
Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

Myeloperoxidase–A bridge linking inflammation and oxidative stress with cardiovascular disease

G Ndrepepa - Clinica chimica acta, 2019 - Elsevier
Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

Inflammation in human heart failure: major mediators and therapeutic targets

M Reina-Couto, P Pereira-Terra… - Frontiers in …, 2021 - frontiersin.org
Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Established and emerging roles of biomarkers in heart failure

NE Ibrahim, JL Januzzi Jr - Circulation research, 2018 - Am Heart Assoc
Heart failure (HF) is a complex syndrome with an enormous societal burden in terms of cost,
morbidity, and mortality. Natriuretic peptide testing is now widely used to support diagnosis …

Early increases in multiple biomarkers predict subsequent cardiotoxicity in patients with breast cancer treated with doxorubicin, taxanes, and trastuzumab

B Ky, M Putt, H Sawaya, B French, JL Januzzi… - Journal of the American …, 2014 - jacc.org
Objectives: The aim of this study was to determine if individual or multiple biomarkers are
associated with cardiotoxicity in patients with breast cancer undergoing cancer therapy …

The role of biomarkers in cardio-oncology

K Ananthan, AR Lyon - Journal of cardiovascular translational research, 2020 - Springer
In the field of cardio-oncology, it is well recognised that despite the benefits of chemotherapy
in treating and possibly curing cancer, it can cause catastrophic damage to bystander …

Utility of the neutrophil to lymphocyte ratio in predicting long-term outcomes in acute decompensated heart failure

S Uthamalingam, EA Patvardhan… - The American journal of …, 2011 - Elsevier
Neutrophil-to-lymphocyte ratio (NLR) has been associated with poor outcomes in patients
with acute coronary syndromes. However, its role for risk stratification in acute …

[HTML][HTML] Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are predictors of heart failure

E Durmus, T Kivrak, F Gerin, M Sunbul, I Sari… - Arquivos brasileiros de …, 2015 - SciELO Brasil
Background: Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR)
are inflammatory markers used as prognostic factors in various diseases. The aims of this …

BNP and NT-proBNP as prognostic markers in persons with acute decompensated heart failure: a systematic review

PL Santaguida, AC Don-Wauchope, M Oremus… - Heart failure …, 2014 - Springer
A systematic review was undertaken to examine the evidence for B-type natriuretic peptides
(BNP and NT-proBNP) as independent predictors of mortality, morbidity, or combined …

Biomarkers in heart failure: the past, current and future

M Sarhene, Y Wang, J Wei, Y Huang, M Li, L Li… - Heart failure …, 2019 - Springer
Despite the enhanced knowledge of the pathophysiology of heart failure (HF), it still remains
a serious syndrome with substantial morbidity, mortality, and frequent hospitalizations …