Current challenges and best-practice protocols for microbiome analysis

R Bharti, DG Grimm - Briefings in bioinformatics, 2021 - academic.oup.com
Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

Application of metagenomics to biological wastewater treatment

G Chen, R Bai, Y Zhang, B Zhao, Y Xiao - Science of The Total …, 2022 - Elsevier
Biological wastewater treatment is a process in which the microbial metabolism of complex
communities transforms pollutants into low-or non-toxic products. Due to the absence of an …

Comparison of normalization methods for the analysis of metagenomic gene abundance data

MB Pereira, M Wallroth, V Jonsson, E Kristiansson - BMC genomics, 2018 - Springer
Background In shotgun metagenomics, microbial communities are studied through direct
sequencing of DNA without any prior cultivation. By comparing gene abundances estimated …

A review of normalization and differential abundance methods for microbiome counts data

D Swift, K Cresswell, R Johnson… - Wiley …, 2023 - Wiley Online Library
The recent development of cost‐effective high‐throughput DNA sequencing technologies
has tremendously increased microbiome research. However, it has been well documented …

Statistical normalization methods in microbiome data with application to microbiome cancer research

Y Xia - Gut Microbes, 2023 - Taylor & Francis
Mounting evidence has shown that gut microbiome is associated with various cancers,
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …

Identification and reconstruction of novel antibiotic resistance genes from metagenomes

F Berglund, T Österlund, F Boulund, NP Marathe… - Microbiome, 2019 - Springer
Background Environmental and commensal bacteria maintain a diverse and largely
unknown collection of antibiotic resistance genes (ARGs) that, over time, may be mobilized …

A comprehensive survey of integron-associated genes present in metagenomes

M Buongermino Pereira, T Österlund, KM Eriksson… - BMC genomics, 2020 - Springer
Background Integrons are genomic elements that mediate horizontal gene transfer by
inserting and removing genetic material using site-specific recombination. Integrons are …

HMDB: A curated database of genes involved in hydrocarbon monooxygenation reaction with homologous genes as background

S Wang, Y Yun, X Tian, Z Su, Z Liao, G Li… - Journal of Hazardous …, 2023 - Elsevier
The investigation of hydrocarbon degradation potential of environmental microorganisms is
an important research topic, whether for the global carbon cycle or oil pollution remediation …

Optimal permutation recovery in permuted monotone matrix model

R Ma, T Tony Cai, H Li - Journal of the American Statistical …, 2021 - Taylor & Francis
Motivated by recent research on quantifying bacterial growth dynamics based on genome
assemblies, we consider a permuted monotone matrix model Y= Θ Π+ Z, where the rows …

The state of play of reproducibility in statistics: an empirical analysis

X Xiong, I Cribben - The American Statistician, 2023 - Taylor & Francis
Reproducibility, the ability to reproduce the results of published papers or studies using their
computer code and data, is a cornerstone of reliable scientific methodology. Studies where …