[HTML][HTML] Diagnostic and therapeutic advances in adults with acute lymphoblastic leukemia in the era of gene analysis and targeted immunotherapy
JH Yoon, S Lee - The Korean Journal of Internal Medicine, 2024 - ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is one of the most rapidly changing hematological
malignancies with advanced understanding of the genetic landscape, detection methods of …
malignancies with advanced understanding of the genetic landscape, detection methods of …
PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia
K Shah, A Nasimian, M Ahmed, L Al Ashiri… - Blood Cancer …, 2023 - nature.com
The deregulation of BCL2 family proteins plays a crucial role in leukemia development.
Therefore, pharmacological inhibition of this family of proteins is becoming a prevalent …
Therefore, pharmacological inhibition of this family of proteins is becoming a prevalent …
[HTML][HTML] Notch inhibitors and BH3 mimetics in T-cell acute lymphoblastic leukemia
I Sergio, C Varricchio, F Squillante… - International Journal of …, 2024 - mdpi.com
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy
with poor response to conventional therapy, derived from hematopoietic progenitors …
with poor response to conventional therapy, derived from hematopoietic progenitors …
AlphaML: A clear, legible, explainable, transparent, and elucidative binary classification platform for tabular data
Leveraging the potential of machine learning and recognizing the broad applications of
binary classification, it becomes essential to develop platforms that are not only powerful but …
binary classification, it becomes essential to develop platforms that are not only powerful but …
Targeting LMO2-induced autocrine FLT3 signaling to overcome chemoresistance in early T-cell precursor acute lymphoblastic leukemia
Abstract Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) is an immature
subtype of T-cell acute lymphoblastic leukemia (T-ALL) commonly show deregulation of the …
subtype of T-cell acute lymphoblastic leukemia (T-ALL) commonly show deregulation of the …
Synergistic Effect of Venetoclax and Bendamustine in Early T-cell Precursor Acute Lymphoblastic Leukemia
HDT Nguyen, TM Le, D Lee, HJ Cho, J Lee, SK Sohn… - in vivo, 2024 - iv.iiarjournals.org
Background/Aim: To date, therapeutic options for T-cell acute lymphoblastic leukemia (T-
ALL) remain very limited. This study evaluated the efficacy of monotherapies and …
ALL) remain very limited. This study evaluated the efficacy of monotherapies and …