Systematic benchmarking of statistical methods to assess differential expression of circular RNAs

A Buratin, S Bortoluzzi, E Gaffo - Briefings in bioinformatics, 2023 - academic.oup.com
Circular RNAs (circRNAs) are covalently closed transcripts involved in critical regulatory
axes, cancer pathways and disease mechanisms. CircRNA expression measured with RNA …

Functional long non-coding and circular RNAs in zebrafish

G Ranjan, P Sehgal, D Sharma, V Scaria… - Briefings in …, 2021 - academic.oup.com
The utility of model organisms to understand the function of a novel transcript/genes has
allowed us to delineate their molecular mechanisms in maintaining cellular homeostasis …

Developmental programming: prenatal testosterone excess on liver and muscle coding and noncoding RNA in female sheep

N Saadat, M Puttabyatappa, VR Elangovan… - …, 2022 - academic.oup.com
Prenatal testosterone (T)-treated female sheep manifest peripheral insulin resistance,
ectopic lipid accumulation, and insulin signaling disruption in liver and muscle. This study …

Genome-wide identification and analysis of the methylation of lncRNAs and prognostic implications in the glioma

Y He, L Wang, J Tang, Z Han - Frontiers in Oncology, 2021 - frontiersin.org
Glioma is characterized by rapid cell proliferation and extensive infiltration among brain
tissues, but the molecular pathology has been still poorly understood. Previous studies …

Skeletal muscle lncRNA profile associated with fatty acids in beef cattle

BM Salatta, MMM Muniz, LFS Fonseca, LFM Mota… - 2024 - researchsquare.com
This study aimed to identify differentially expressed (DE) long non-coding RNAs (lncRNAs)
in muscle tissue of Nellore cattle clustered by their fatty acid profile. Longissimus thoracis …

[PDF][PDF] Systematic benchmarking of bulk and single-cell RNA-seq statistical methods to assess differential expression of circular RNAs

A Buratin, S Bortoluzzi, E Gaffo - 2022 - researchgate.net
Abstract Background Circular RNAs (circRNAs) are transcripts with covalently joined 3'and
5'ends. They play critical regulatory roles, are involved in disease and cancer mechanisms …

lncRNA Mediated Hijacking of T-cell Hypoxia Response Pathway by Mycobacterium tuberculosis Predicts Latent to Active Progression in Humans

J Mehra, V Kumar, P Srivastava, T Sethi - bioRxiv, 2020 - biorxiv.org
Cytosolic functions of Long non-coding RNAs including mRNA translation masking and
sponging are major regulators of biological pathways. Formation of T cell-bounded hypoxic …

Statistical methods for testing differential gene expression in bulk and single-cell RNA sequencing data

AT Assefa - 2020 - biblio.ugent.be
The transcriptome is the complete set of RNA molecules in biological samples, and they are
primarily invariant in different tissues and cells of the same individual. Studying the …

[HTML][HTML] Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease

JL Johnson, D Sargsyan, EM Neiman, A Hart… - JCI insight, 2024 - ncbi.nlm.nih.gov
The role of long noncoding RNAs (lncRNAs) in disease is incompletely understood, but their
regulation of inflammation is increasingly appreciated. We addressed the extent of lncRNA …