2H/4H-Chromenes—A versatile biologically attractive Scaffold

V Raj, J Lee - Frontiers in Chemistry, 2020 - frontiersin.org
2H/4H-chromene (2H/4H-ch) is an important class of heterocyclic compounds with versatile
biological profiles, a simple structure, and mild adverse effects. Researchers discovered …

Isocyanide-based multicomponent reactions for the synthesis of benzopyran derivatives with biological scaffolds

MT Nazeri, T Nasiriani, S Torabi… - Organic & Biomolecular …, 2024 - pubs.rsc.org
Benzopyrans (BZPs) are one of the most privileged and influential small O-heterocycles that
form the core of many natural compounds, commercial drugs, biological compositions …

Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic …

M Almaghrabi, A Musa, AKB Aljohani… - Journal of …, 2024 - Taylor & Francis
Microbiological DNA gyrase is recognized as an exceptional microbial target for the
innovative development of low-resistant and more effective antimicrobial drugs. Hence, we …

Introducing novel potent anticancer agents of 1H-benzo[f]chromene scaffolds, targeting c-Src kinase enzyme with MDA-MB-231 cell line anti-invasion effect

HEA Ahmed, MAA El-Nassag, AH Hassan… - Journal of Enzyme …, 2018 - Taylor & Francis
In our effort to develop novel and powerful agents with anti-proliferative activity, two new
series of 1 H-benzo [f] chromene derivatives, 4a–h and 6a–h, were synthesised using …

Nonorthogonal Cascade Catalysis in Multicompartment Micelles

E Ahmed, J Cho, SS Jang… - Chemistry–A European …, 2023 - Wiley Online Library
Multicompartment micelles (MCMs) containing acid and base sites in discrete domains are
prepared from poly (norbornene)‐based amphiphilic bottlebrush copolymers in aqueous …

Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against …

EKA Abdelall, HAH Elshemy, MB Labib… - Bioorganic …, 2022 - Elsevier
In this study, three novel sets of 4-aryl-4H-chromene derivatives 4a–c, 6a–d and 7a–c were
synthesized and evaluated for anticancer activity. Characterization of new compounds was …

A New Family of Benzo[h]Chromene Based Azo Dye: Synthesis, In-Silico and DFT Studies with In Vitro Antimicrobial and Antiproliferative Assessment

AS Abd-El-Aziz, A Alsaggaf, E Assirey, A Naqvi… - International Journal of …, 2021 - mdpi.com
The high biological activity of the chromene compounds coupled with the intriguing optical
features of azo chromophores prompted our desire to construct novel derivatives of …

Novel chromenes and benzochromenes bearing arylazo moiety: molecular docking, in-silico admet, in-vitro antimicrobial and anticancer screening

TH Afifi, SM Riyadh, AA Deawaly, A Naqvi - Medicinal Chemistry …, 2019 - Springer
Novel derivatives of benzochromene 9a–e and chromene 10a–e were synthesized via multi
components reaction that utilizes azo dyes, malononitrile, and arylaldehydes as starting …

[PDF][PDF] Synthesis and antioxidant activity of some novel 4H-chromene derivatives catalysed by biogenic tin oxide nanoparticles

MS Gari, BP Narasaiah… - … Res. Appl. Chem, 2023 - biointerfaceresearch.com
The present study reports an eco-friendly and biogenic synthesis of Tin Oxide Nanoparticles
(SnO2 NPs) using aqueous sunflower leaf extract. The synthesized SnO2 NPs were …

Targeted potent antimicrobial and antitumor oxygen-heterocyclic-based pyran analogues: synthesis and computational studies

AHFA El-Wahab, RM Borik, AAM Al-Dies, AM Fouda… - Scientific Reports, 2024 - nature.com
The process of creating a series of 3-amino-1-aryl-8-methoxy-1 H-benzo [f] chromene-2-
carbonitriles (4a-q) involved reacting 6-methoxynaphthalen-2-ol (1), the appropriate …