The architectures of iterative type I PKS and FAS

DA Herbst, CA Townsend, T Maier - Natural product reports, 2018 - pubs.rsc.org
Covering: up to mid of 2018 Type I fatty acid synthases (FASs) are giant multienzymes
catalyzing all steps of the biosynthesis of fatty acids from acetyl-and malonyl-CoA by iterative …

Ochratoxin A: General overview and actual molecular status

A El Khoury, A Atoui - Toxins, 2010 - mdpi.com
Ochratoxin A (OTA) is a mycotoxin produced by several species of Aspergillus and
Penicillium fungi that structurally consists of a para-chlorophenolic group containing a …

Natural products of filamentous fungi: enzymes, genes, and their regulation

D Hoffmeister, NP Keller - Natural product reports, 2007 - pubs.rsc.org
Covering: up to June 2006We review the literature on the enzymes, genes, and whole gene
clusters underlying natural product biosyntheses and their regulation in filamentous fungi …

Ochratoxin A producing fungi, biosynthetic pathway and regulatory mechanisms

Y Wang, L Wang, F Liu, Q Wang, JN Selvaraj, F Xing… - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA), mainly produced by Aspergillus and Penicillum species, is one of the
most important mycotoxin contaminants in agricultural products. It is detrimental to human …

Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets

RJ Cox - Organic & biomolecular chemistry, 2007 - pubs.rsc.org
Fungi produce a wide variety of biologically active compounds. Among these, the
polyketides form a large and structurally diverse group. These compounds are synthesised …

Phylogenomic analysis of type I polyketide synthase genes in pathogenic and saprobic ascomycetes

S Kroken, NL Glass, JW Taylor… - Proceedings of the …, 2003 - National Acad Sciences
Fungal type I polyketides (PKs) are synthesized by PK synthases (PKSs) and include well
known secondary metabolites such as the anticholesterol drug lovastatin and the potent …

Complete reconstitution of a highly reducing iterative polyketide synthase

SM Ma, JWH Li, JW Choi, H Zhou, KKM Lee… - Science, 2009 - science.org
Highly reducing iterative polyketide synthases are large, multifunctional enzymes that make
important metabolites in fungi, such as lovastatin, a cholesterol-lowering drug from …

Navigating the fungal polyketide chemical space: from genes to molecules

YH Chooi, Y Tang - The Journal of organic chemistry, 2012 - ACS Publications
The iterative type I polyketide synthases (IPKSs) are central to the biosynthesis of an
enormously diverse array of natural products in fungi. These natural products, known as …

Secondary metabolites from entomopathogenic Hypocrealean fungi

I Molnár, DM Gibson, SB Krasnoff - Natural product reports, 2010 - pubs.rsc.org
Covering: up to the end of February 2010 This review surveys the natural products
described from entomopathogenic Hypocrealean fungi, including their structures, biological …

A Putative Polyketide Synthase/Peptide Synthetase from Magnaporthe grisea Signals Pathogen Attack to Resistant Rice

HU Böhnert, I Fudal, W Dioh, D Tharreau… - The Plant …, 2004 - academic.oup.com
Isolates of the rice blast fungus Magnaporthe grisea that carry the gene encoding Avirulence
Conferring Enzyme1 (ACE1) are specifically recognized by rice (Oryza sativa) cultivars …