A metabolic and functional overview of brain aging linked to neurological disorders

NZ Baquer, A Taha, P Kumar, P McLean, SM Cowsik… - Biogerontology, 2009 - Springer
Close correlations have recently been shown among the late onset complications
encountered in diabetes and aging linked to neurobiological disorders. Aging in females …

Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic …

F Ding, J Yao, JR Rettberg, S Chen, RD Brinton - PloS one, 2013 - journals.plos.org
We previously demonstrated that mitochondrial bioenergetic deficits in the female brain
accompanied reproductive senescence and was accompanied by a shift from an aerobic …

[HTML][HTML] Neuroimmunomodulation by estrogen in health and disease

HP Priyanka, RS Nair - AIMS neuroscience, 2020 - ncbi.nlm.nih.gov
Systemic homeostasis is maintained by the robust bidirectional regulation of the
neuroendocrine-immune network by the active involvement of neural, endocrine and …

Administration of estradiol and progesterone modulate the activities of antioxidant enzyme and aminotransferases in naturally menopausal rats

K Moorthy, D Sharma, SF Basir, NZ Baquer - Experimental gerontology, 2005 - Elsevier
In aging tissues the oxidative stress increases due to decreased activity of antioxidant
enzymes and proteolysis increases due to decreased activity of aminotransferases, which …

[HTML][HTML] The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice: potential molecular mechanisms

L Lundholm, G Bryzgalova, H Gao… - Journal of …, 2019 - joe.bioscientifica.com
The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in
ob/ob mice: potential molecular mechanisms in: Journal of Endocrinology Volume 243 Issue 2 …

Estrogen-induced neuroprotective and anti-inflammatory effects are dependent on the brain areas of middle-aged female rats

UP Pratap, A Patil, HR Sharma, L Hima… - Brain research …, 2016 - Elsevier
Background Reproductive aging in females is characterized by fluctuations and precipitous
decline in estrogen levels, which may lead to reduction in cognitive function and age …

Influence of menstrual cycle on muscle glycogen utilization during high-intensity intermittent exercise until exhaustion in healthy women

T Matsuda, H Takahashi, M Nakamura… - Applied Physiology …, 2022 - cdnsciencepub.com
The present study investigated the effects of the menstrual cycle on muscle glycogen and
circulating substrates during high-intensity intermittent exercise until exhaustion in healthy …

Myelin pathogenesis and functional deficits following SCI are age-associated

MM Siegenthaler, DL Ammon, HS Keirstead - Experimental neurology, 2008 - Elsevier
Most spinal cord injuries (SCI) occur in young adults. In the past few decades however, the
average age at time of SCI and the percentage of injuries in persons over the age of 60 have …

Estradiol and progesterone treatments change the lipid profile in naturally menopausal rats from different age groups

K Moorthy, UCS Yadav, AK Mantha, SM Cowsik… - Biogerontology, 2004 - Springer
The effect of estradiol and progesterone therapy in serum and liver on the lipid profile of
naturally menopausal albino rats of the Wistar strain of different age groups (12, 18 and …

Estradiol Modulates Membrane‐Linked ATPases, Antioxidant Enzymes, Membrane Fluidity, Lipid Peroxidation, and Lipofuscin in Aged Rat Liver

P Kumar, RK Kale, NZ Baquer - Journal of aging research, 2011 - Wiley Online Library
Free radical production and oxidative stress are known to increase in liver during aging, and
may contribute to the oxidative damage. These changes increase during menopausal …