Wearable and implantable devices for drug delivery: Applications and challenges

A Kar, N Ahamad, M Dewani, L Awasthi, R Patil… - Biomaterials, 2022 - Elsevier
Poor adherence to drug dosing schedule is responsible for∼ 50% of hospitalization cases.
Most patients fail to adhere to a strict dosing schedule due to invasive drug administration …

[HTML][HTML] Solid implantable devices for sustained drug delivery

E Magill, S Demartis, E Gavini, AD Permana… - Advanced Drug Delivery …, 2023 - Elsevier
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug
administration routes. Oral and injectable drug administration are the most common routes …

Long-acting antiretrovirals: a new era for the management and prevention of HIV infection

P Thoueille, E Choong, M Cavassini… - Journal of …, 2022 - academic.oup.com
The long-acting antiretroviral cabotegravir and rilpivirine combination has just received FDA,
EMA and Health Canada approval. This novel drug delivery approach is about to …

Advanced implantable drug delivery technologies: transforming the clinical landscape of therapeutics for chronic diseases

FP Pons-Faudoa, A Ballerini, J Sakamoto… - Biomedical …, 2019 - Springer
Chronic diseases account for the majority of all deaths worldwide, and their prevalence is
expected to escalate in the next 10 years. Because chronic disorders require long-term …

Carbon fiber reinforced polymers for implantable medical devices

CYX Chua, HC Liu, N Di Trani, A Susnjar, J Ho… - Biomaterials, 2021 - Elsevier
Carbon fibers reinforced polymers (CFRPs) are prolifically finding applications in the
medical field, moving beyond the aerospace and automotive industries. Owing to its high …

Long-acting HIV pre-exposure prophylaxis (PrEP) approaches: recent advances, emerging technologies, and development challenges

V Agrahari, SM Anderson, MM Peet… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Poor or inconsistent adherence to daily oral pre-exposure prophylaxis (PrEP)
has emerged as a key barrier to effective HIV prevention. The advent of potent long-acting …

Microarray patches: breaking down the barriers to contraceptive care and HIV prevention for women across the globe

AJ Paredes, IK Ramöller, PE McKenna… - Advanced Drug Delivery …, 2021 - Elsevier
Despite the existence of a variety of contraceptive products for women, as well as decades
of research into the prevention and treatment of human immunodeficiency virus (HIV), there …

3D-printed implantable devices with biodegradable rate-controlling membrane for sustained delivery of hydrophobic drugs

CJ Picco, J Domínguez-Robles, E Utomo… - Drug Delivery, 2022 - Taylor & Francis
Implantable drug delivery systems offer an alternative for the treatments of long-term
conditions (ie schizophrenia, HIV, or Parkinson's disease among many others). The …

[HTML][HTML] 3D-printed reservoir-type implants containing poly (lactic acid)/poly (caprolactone) porous membranes for sustained drug delivery

A Korelidou, J Domínguez-Robles, ER Magill… - Biomaterials …, 2022 - Elsevier
Implantable drug delivery systems are an interesting alternative to conventional drug
delivery systems to achieve local or systemic drug delivery. In this work, we investigated the …

Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles

DA Cobb, N Smith, S Deodhar, AN Bade… - Nature …, 2021 - nature.com
Abstract Treatment and prevention of human immunodeficiency virus type one (HIV-1)
infection was transformed through widespread use of antiretroviral therapy (ART). However …