[HTML][HTML] Singling out motor neurons in the age of single-cell transcriptomics
Motor neurons are a remarkably powerful cell type in the central nervous system. They
innervate and control the contraction of virtually every muscle in the body and their …
innervate and control the contraction of virtually every muscle in the body and their …
Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration
H Liu, L Guan, M Deng, L Bolund… - Frontiers in …, 2023 - frontiersin.org
Introduction The gradual loss of motor neurons (MNs) in the brain and spinal cord is a
hallmark of amyotrophic lateral sclerosis (ALS), but the mechanisms underlying …
hallmark of amyotrophic lateral sclerosis (ALS), but the mechanisms underlying …
Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling
MM Sartoretti, CA Campetella, GM Lanuza - Development, 2022 - journals.biologists.com
Significant progress has been made in elucidating the basic principles that govern neuronal
specification in the developing central nervous system. In contrast, much less is known …
specification in the developing central nervous system. In contrast, much less is known …
Integrative genetic and single cell RNA sequencing analysis provides
K Kristiansen, J Zhang, Y Luo - Methods and Applications in …, 2024 - books.google.com
Methods: Based on 75 ALS-pathogenicity/susceptibility genes and large-scale single-cell
transcriptomes of human/mouse brain/spinal cord/muscle tissues, we performed an …
transcriptomes of human/mouse brain/spinal cord/muscle tissues, we performed an …