With the ability to transport cargo molecules across cell membranes with low toxicity, cell-
penetrating peptides (CPPs) have become promising candidates for next generation peptide …

The advantages of targeted therapy have motivated many efforts to find distinguishing
features between the molecular cell surface landscapes of diseased and normal cells …

Abstract pHLIPs are a family of soluble∼ 36 amino acid peptides, which bind to membrane
surfaces. If the environment is acidic, a pHLIP folds and inserts across the membrane to form …

Protein aggregation, involving the formation of dimers, oligomers, and fibrils, is associated
with many human diseases. Type 2 diabetes is one of the common amyloidosis and linked …

Fullerenols have garnered significant scientific interest in nano-technology and biomedicine.
A detailed understanding of their interactions with proteins is fundamentally important for …

The pH (low) insertion peptides (pHLIPs) is a family of peptides that are able to insert into a
lipid bilayer at acidic pH. The molecular mechanism of pHLIPs insertion, folding, and stability …

The investigation of the interaction of peptides with cell membranes is the focus of active
research. It can enhance the understanding of basic membrane functions such as …

Peptides with the ability to bind and insert into the cell membrane have immense potential in
biomedical applications. pH (low) insertion peptide (pHLIP), a water-soluble polypeptide …

After the synthesis of transmembrane peptides/proteins (TMPs), their insertion into a lipid
bilayer is a fundamental biophysical process. Moreover, correct orientations of TMPs in …

Despite their presence in many aspects of biology, the study of membrane proteins lags
behind that of their soluble counterparts. Improving structural analysis of membrane proteins …