Treatment of Bacterial Infections with β-Lactams: Cooperation with Innate Immunity

M Mondemé, C Carnoy, JC Sirard… - Infection and …, 2023 - Am Soc Microbiol
ABSTRACT β-Lactams are the most widely prescribed antibiotics used for the control and
treatment of bacterial infections. The direct effect of β-lactams on bacteria is well studied …

Omadacycline in treating community-based infections: a review and expert perspective

G Sakoulas, M Nowak, M Geriak - Expert Review of Anti-infective …, 2023 - Taylor & Francis
Introduction Omadacycline is approved for the treatment of community-acquired bacterial
pneumonia (CABP) and acute bacterial skin and soft tissue infection (ABSSSI). The …

Comparative effectiveness of first-line and alternative antibiotic regimens in hospitalized patients with nonsevere community-acquired pneumonia: a multicenter …

AD Bai, S Srivastava, BKC Wong, GC Digby, F Razak… - Chest, 2024 - Elsevier
Background There are several antibiotic regimens to treat community-acquired pneumonia
(CAP). Research Question In patients hospitalized to a non-ICU ward setting with CAP, is …

β-Lactams plus doxycycline versus azithromycin for treatment of severe community-acquired pneumonia in critically ill patients

A Greco Kinney, N Kovacic Scherrer… - Journal of …, 2023 - academic.oup.com
Objectives Community-acquired pneumonia (CAP) is a significant source of hospital
admissions and mortality. Atypical organisms are implicated in up to 40% of cases of CAP …

Controversies in the management of community-acquired pneumonia in adults

E Tucker, M O'Sullivan, L Waddell - Australian Prescriber, 2024 - pmc.ncbi.nlm.nih.gov
Community-acquired pneumonia (CAP) is a common infectious syndrome in Australia and a
leading global cause of morbidity and mortality. It drives a significant amount of antimicrobial …

[HTML][HTML] Beta-lactam plus macrolide for patients hospitalized with community-acquired pneumonia: Difference between autumn and spring

Y Kim, Y Jeon, KT Kwon, S Bae… - Journal of Korean …, 2022 - synapse.koreamed.org
Background The 2017 Korean guideline on community-acquired pneumonia (CAP)
recommended beta-lactam plus macrolide combination therapy for patients hospitalized with …

Appropriateness of antimicrobial selection for treatment of pneumonia in selected public hospitals of Eastern Ethiopia: A cross-sectional study

A Jambo, D Edessa, F Adem… - SAGE Open …, 2023 - journals.sagepub.com
Objective: Inappropriate antimicrobial use leads to drug resistance and poor clinical
outcomes. Considering the lack of data regarding the drug use patterns in the treatment of …

Clinical Effectiveness and Outcomes of Azithromycin versus Doxycycline Containing Regimen in Inpatients with Community Acquired Pneumonia: A Retrospective …

AS Babonji, SJ Alshehri… - Journal of Clinical …, 2023 - Wiley Online Library
Background. Community acquired pneumonia (CAP) is a common serious infection that is
usually treated with a macrolide with a β‐lactam while doxycycline is considered an …

Revisión bibliográfica sobre la efectividad y duración del tratamiento antimicrobiano usado en pacientes mayores a 65 años con neumonía adquirida en la …

RA Macao Guayllazaca - 2024 - dspace.ucuenca.edu.ec
Community-acquired pneumonia is a common respiratory infection, with high morbidity and
mortality in adult patients. The difficulty in etiological diagnosis means that in most cases …

Minocycline Enhances the Antimicrobial Capacity of Unpolarized Macrophages Against Acinetobacter baumannii While Inducing an Anti-inflammatory Profile

A Guerra, W Rose, DR Andes… - Open Forum Infectious …, 2017 - academic.oup.com
Background Acinetobacter baumannii (AB) is a Gram-negative pathogen associated with
high patient morbidity and mortality in nosocomial infections. Limited treatment options are …