Inflammasomes are a group of protein complexes built around several proteins, including
NLRP3, NLRC4, AIM2 and NLRP6. Recognition of a diverse range of microbial, stress and …

Inflammasomes are multiprotein complexes that activate caspase-1, which leads to
maturation of the proinflammatory cytokines interleukin 1β (IL-1β) and IL-18 and the …

Inflammasomes are large cytoplasmic complexes that sense microbial infections/danger
molecules and induce caspase-1 activation-dependent cytokine production and …

Inflammasomes are a set of intracellular protein complexes that enable autocatalytic
activation of inflammatory caspases, which drive host and immune responses by releasing …

The inflammasome is a multiprotein complex that mediates the activation of caspase-1,
which promotes secretion of the proinflammatory cytokines interleukin 1β (IL-1β) and IL-18 …

Inflammasomes are large cytosolic multiprotein complexes that assemble in response to
detection of infection-or stress-associated stimuli and lead to the activation of caspase-1 …

The innate immune system relies on its capacity to rapidly detect invading pathogenic
microbes as foreign and to eliminate them. The discovery of Toll-like receptors (TLRs) …

Inflammasomes activate caspase-1 for processing and secretion of the cytokines interleukin-
1β (IL-1β) and IL-18. Cryopyrin/NALP3/NLRP3 is an essential component of inflammasomes …

Inflammasomes are cytosolic multiprotein complexes that assemble in response to a variety
of infectious and noxious insults. Inflammasomes play a critical role in the initiation of innate …

The innate immune system comprises several classes of pattern recognition receptors,
including Toll-like receptors (TLRs), NOD-like receptors (NLRs), and RIG-1-like receptors …