K Frykholm, V Müller, KK Sriram… - Quarterly Reviews of …, 2022 - cambridge.org
Nanofluidic structures have over the last two decades emerged as a powerful platform for detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …
Efficient capture and rapid detection of pathogenic bacteria from body fluids lead to early diagnostics of bacterial infections and significantly enhance the survival rate. We propose a …
Extracellular vesicles (EVs) are cell-derived membrane structures that circulate in body fluids and show considerable potential for noninvasive diagnosis. EVs possess surface …
M Shayegan, R Tahvildari, K Metera… - Journal of the …, 2019 - ACS Publications
Biomolecular condensates formed by liquid–liquid phase separation of proteins and nucleic acids have been recently discovered to be prevalent in biology. These dynamic …
The high rate of cancer worldwide and the heavy costs imposed on governments and humanity have always motivated researchers to develop point-of-care (POC) biosensors for …
The wormlike-chain model is commonly used to describe the statistical properties of DNA and liquid-crystal polymers. Following the Green's function approach, here we present the …
Confinement of single molecules within nanoscale environments is crucial in a range of fields, including biomedicine, genomics, and biophysics. Here, we present a method that …
In many technological applications, DNA is confined within nanoenvironments that are smaller than the size of the unconfined polymer in solution. However, the dependence of the …
JS Leith, A Kamanzi, D Sean, D Berard… - …, 2016 - ACS Publications
We directly measure the free energy of confinement for semiflexible polymers from the nanoscale to bulk regimes in slit-like confinement. We use convex lens-induced confinement …