Skin plays an important role in mediating our interactions with the world. Recreating the
properties of skin using electronic devices could have profound implications for prosthetics …

Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …

Calcium imaging with genetically encoded calcium indicators (GECIs) is routinely used to
measure neural activity in intact nervous systems. GECIs are frequently used in one of two …

Over the past 10 years, the development and convergence of microbial opsin engineering,
modular genetic methods for cell-type targeting and optical strategies for guiding light …

Techniques for neuromodulation serve as effective routes to care of patients with many types
of challenging conditions. Continued progress in this field of medicine will require (1) …

Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

Activity in motor cortex predicts specific movements seconds before they occur, but how this
preparatory activity relates to upcoming movements is obscure. We dissected the conversion …

Genetically encoded calcium indicators (GECIs) allow measurement of activity in large
populations of neurons and in small neuronal compartments, over times of milliseconds to …

Perceptual decisions involve distributed cortical activity. Does information flow sequentially
from one cortical area to another, or do networks of interconnected areas contribute at the …

There have been two recent revolutionary advances in neuroscience: First, genetically
encoded activity sensors have brought the goal of optical detection of single action …