Toll-like receptors, associated biological roles, and signaling networks in non-mammals

L Nie, SY Cai, JZ Shao, J Chen - Frontiers in immunology, 2018 - frontiersin.org
The innate immune system is the first line of defense against pathogens, which is initiated by
the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

The mucosal immune system of teleost fish

I Salinas - Biology, 2015 - mdpi.com
Teleost fish possess an adaptive immune system associated with each of their mucosal
body surfaces. Evidence obtained from mucosal vaccination and mucosal infection studies …

Beta-glucan: an ideal immunostimulant in aquaculture (a review)

DK Meena, P Das, S Kumar, SC Mandal… - Fish physiology and …, 2013 - Springer
The major hindrance in the development and sustainability of aquaculture industry is the
occurrence of various diseases in the farming systems. Today, preventive and management …

Toll-like receptors in bony fish: from genomics to function

Y Palti - Developmental & Comparative Immunology, 2011 - Elsevier
Receptors that recognize conserved pathogen molecules are the first line of cellular innate
immunity defense. Toll-like receptors (TLRs) are the best understood of the innate immune …

Toll-like receptor recognition of bacteria in fish: ligand specificity and signal pathways

J Zhang, X Kong, C Zhou, L Li, G Nie, X Li - Fish & shellfish immunology, 2014 - Elsevier
Pattern recognition receptors (PRRs) recognize the conserved molecular structure of
pathogens and trigger the signaling pathways that activate immune cells in response to …

Toll-like receptor signaling in bony fish

A Rebl, T Goldammer, HM Seyfert - Veterinary immunology and …, 2010 - Elsevier
The innate immune system constitutes an efficient defense against invading microbial
pathogens. Toll-like receptors (TLRs) eventually alert vertebrates about the presence of …

The antiviral innate immune response in fish: evolution and conservation of the IFN system

C Langevin, E Aleksejeva, G Passoni, N Palha… - Journal of molecular …, 2013 - Elsevier
Innate immunity constitutes the first line of the host defense after pathogen invasion. Viruses
trigger the expression of interferons (IFNs). These master antiviral cytokines induce in turn a …

Molecular regulation of interferon antiviral response in fish

YB Zhang, JF Gui - Developmental & Comparative Immunology, 2012 - Elsevier
Interferon (IFN) response is the first line of host defense against virus infection. The recent
years have witnessed tremendous progress in understanding of fish IFN antiviral response …

Ligand specificities of Toll-like receptors in fish: indications from infection studies

D Pietretti, GF Wiegertjes - Developmental & Comparative Immunology, 2014 - Elsevier
Toll like receptors (TLRs) are present in many different fish families from several different
orders, including cyprinid, salmonid, perciform, pleuronectiform and gadiform …

Expression and functional characterization of the RIG-I-like receptors MDA5 and LGP2 in Rainbow trout (Oncorhynchus mykiss)

M Chang, B Collet, P Nie, K Lester, S Campbell… - Journal of …, 2011 - Am Soc Microbiol
The retinoic acid-inducible gene I (RIG-I)-like receptors (RLR) comprise three homologues:
RIG-I, melanoma differentiation-associated gene 5 (MDA5), and laboratory of genetics and …