[HTML][HTML] Using Computer Modeling and Experimental Methods to Screen for Aptamers That Bind to the VV-GMCSF-LACT Virus

M Dymova, N Vasileva, D Malysheva, A Ageenko… - Molecules, 2024 - mdpi.com
Oncolytic virotherapy is a promising approach for cancer treatment. However, when
introduced into the body, the virus provokes the production of virus-neutralizing antibodies …

SAXS structure studies of the aptamer to the Oncolytic Virus VV-GMCSF-Lact

RV Moryachkov, DO Malysheva, MA Dymova… - 2024 - elib.sfu-kras.ru
Oncolytic viral therapy is a relatively young but rapidly developing area in cancer therapy.
Some viruses can be used to combat cancer cells due to their cytotoxic action, but it is …

Structure Determination of the Pb2+-specific GT Aptamer Using SAXS and Molecular Modeling Methods

PV Artyushenko, IA Shchugoreva, AN Berlina… - 2024 - elib.sfu-kras.ru
Aptamer GT conjugated with gold nanoparticles is specific for heavy metal ions and can be
used for water quality control and environmental monitoring. Circular dichroism (CD) and …