Type 2 diabetes mellitus (T2DM) is a complex disease caused by the interaction between
genetic and environmental factors. A growing number of evidence suggests that the …

Neovascular eye diseases, including retinopathy of prematurity, diabetic retinopathy, and
age-related macular degeneration, threaten the visual health of children and adults. Current …

Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the
main cause of blindness among the people in productive age. The purpose of this literature …

Clinical risk factors for diabetic retinopathy (DR), such as duration of disease and degree of
glucose control, do not adequately predict disease progression in individual patients …

Abstract Background Type 2 diabetes (T2DM) prevalence has been rapidly increasing in the
last decades. T2DM pathogenesis is related to insulin resistance and beta-cell dysfunction …

Diabetic retinopathy (DR) is a major complication of diabetes mellitus, and is the leading
cause of blindness in working-age people. Usually, DR progresses from the asymptomatic …

In the present study we determined the association of angiotensin converting enzyme (ACE)
and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms with diabetic retinopathy …

Abstract Objective Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) gene is one of the
possible genes linking diabetes mellitus (DM) with coronary artery disease (CAD). The aim …

Retinopathy is one of the most devastating complications of diabetes, which a patient fears
the most. Hyperglycemic environment results in many structural, functional, molecular and …

A genome-wide association study had showed G-protein–coupled receptor kinase 5 (GRK5)
rs10886471 was related to the risk of type 2 diabetes mellitus (T2DM) through upregulated …