The lymphatic system is comprised of a network of vessels interrelated with lymphoid tissue,
which has the holistic function to maintain the local physiologic environment for every cell in …

Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Spleen tyrosine kinase (SYK) is known to have a crucial role in adaptive immune receptor
signalling. However, recent reports indicate that SYK also mediates other, unexpectedly …

Abstract The World Health Organization (WHO) has documented that cancer is the second
foremost reason for death worldwide. Various factors are responsible for cancer, for …

Blood vessels and lymphatic vessels form extensive networks that are essential for the
transport of fluids, gases, macromolecules and cells within the large and complex bodies of …

The growth of lymphatic vessels (lymphangiogenesis) is actively involved in a number of
pathological processes including tissue inflammation and tumor dissemination but is …

The mammalian intestine is richly supplied with lymphatic vasculature, which has functions
ranging from maintenance of interstitial fluid balance to transport of antigens, antigen …

The lymphatic vasculature forms a vessel network that drains interstitial fluid from tissues
and returns it to the blood. Lymphatic vessels are also an essential part of the body's …

Podoplanin (PDPN) is a well-conserved, mucin-type transmembrane protein expressed in
multiple tissues during ontogeny and in adult animals, including the brain, heart, kidney …

Emerging evidence suggests that bone marrow–derived endothelial, hematopoietic stem
and progenitor cells contribute to tissue vascularization during both embryonic and postnatal …