With the development in tissue engineering, cell transplantation, and genetic technologies,
living cells have become an important therapeutic tool in clinical medical care. For various …

Regardless of their tissue of origin, multipotent mesenchymal stromal cells (MSCs) are
commonly expanded in vitro for several population doublings to achieve a sufficient number …

This paper discusses the challenges of producing CAR-T cells for cancer treatment and the
potential for Artificial Intelligence (AI) for its improvement. CAR-T cell therapy was approved …

The development of a versatile sensing strategy for the damage-free characterization of
cultured cells is of great importance for both fundamental biological research and industrial …

Patient-specific therapies require that cells be manufactured in multiple batches of small
volumes, making it a challenge for conventional modes of quality control. The added …

Immune therapy for cancer patients is a new and promising area that in the future may
complement traditional chemotherapy. The cell expansion phase is a critical part of the …

What You Will Learn in This Chapter When starting to work with 3D cell cultures it is
essential to be aware of the differences to common 2D cultures in terms of expenses and …

Cell therapy uses live cells to treat diseases. For example, chimeric antigen receptor T cells
(CAR-T) are T cells that have been engineered to express CARs to produce a cytotoxic …

Gene therapy products have tremendous therapeutic potential for indications such as cancer
and even curative potential for some genetic diseases. Most of today's gene therapy …