LncRNAs at the heart of development and disease

KM Anderson, DM Anderson - Mammalian Genome, 2022 - Springer
Abstract Long noncoding RNAs (LncRNAs) have emerged as a diverse class of functional
molecules that contribute to nearly every facet of mammalian cardiac development and …

piRNAs as modulators of disease pathogenesis

KJ Rayford, A Cooley, JT Rumph, A Arun… - International Journal of …, 2021 - mdpi.com
Advances in understanding disease pathogenesis correlates to modifications in gene
expression within different tissues and organ systems. In depth knowledge about the …

Single-Cell Mapping of Large and Small Arteries During Hypertensive Aging

J Cheng, H Wu, C Xie, Y He, R Mou… - The Journals of …, 2024 - academic.oup.com
Vascular aging is directly related to several major diseases including clinical primary
hypertension. Conversely, elevated blood pressure itself accelerates vascular senescence …

In silico selection of an aptamer for the design of aptamer–modified magnetic beads bearing ferrocene co–immobilized label for capacitive detection of acetamiprid

FK Algethami, A Rabti, M Mastouri, SB Aoun… - Talanta, 2023 - Elsevier
In silico evaluation of aptamer/target interactions can facilitate the development of efficient
biosensor with high specificity and affinity. In this work, we present in silico, ie structural …

[HTML][HTML] Targeting a cardiac abundant and fibroblasts-specific piRNA (CFRPi) to attenuate and reverse cardiac fibrosis in pressure-overloaded heart failure

B Chen, B Shi, Z Zhou, Y Cui, G Zeng, L Cheng… - Translational …, 2024 - Elsevier
Cardiac fibrosis under chronic pressure overload is an end-stage adverse remodeling of
heart. However, current heart failure treatments barely focus on anti-fibrosis and the effects …

Differential expression and correlation of immunoregulation related piRNA in rheumatoid arthritis

R Ren, H Tan, Z Huang, Y Wang, B Yang - Frontiers in Immunology, 2023 - frontiersin.org
Background Although PIWI-interacting RNAs (piRNAs) have recently been associated with
germline development and many human diseases, their expression pattern and relationship …

PiRNA pathway in the cardiovascular system: a novel regulator of cardiac differentiation, repair and regeneration

Y Zhou, Y Fang, C Dai, Y Wang - Journal of Molecular Medicine, 2021 - Springer
Piwi-interacting RNAs (piRNAs) are a novel group of small non-coding RNA molecules with
lengths of 21–35 nucleotides, first identified from the germline. PiRNAs and their associated …

A novel piwi-interacting RNA associates with type 2–high asthma phenotypes

J Li, X Hong, M Jiang, AT Kho, A Tiwari… - Journal of Allergy and …, 2024 - Elsevier
Background Piwi-interacting RNAs (piRNAs), comprising the largest noncoding RNA group,
regulate transcriptional processes. Whether piRNAs are associated with type 2 (T2)-high …

Roles of noncoding RNAs in the initiation and progression of myocardial ischemia–reperfusion injury

X Bai, R Niu, J Liu, X Pan, F Wang, W Yang, L Wang… - …, 2021 - Taylor & Francis
The morbidity and mortality of myocardial ischemia–reperfusion injury (MIRI) have increased
in modern society. Noncoding RNAs (ncRNAs), including lncRNAs, circRNAs, piRNAs and …

PIWI‐interacting RNAs and human testicular function

G Saritas, AM Main, SB Winge… - WIREs mechanisms …, 2022 - Wiley Online Library
Small noncoding RNAs (sncRNAs) are pieces of RNA with a length below 200 bp and
represent a diverse group of RNAs having many different biological functions. The best …