Tight spatiotemporal regulation of intracellular Ca2+ plays a critical role in regulating diverse
cellular functions including cell survival, metabolism, and transcription. As a result …

Intracellular Ca2+ dysregulation is a key marker in septic cardiac dysfunction; however,
regulation of the classic Ca2+ regulatory modules cannot successfully abolish this symptom …

Vascular calcification is accelerated in patients with diabetes mellitus and increases risk of
cardiovascular events and mortality. Vascular smooth muscle cells (VSMC) play a key role in …

Background Doxorubicin (DOX) is an anticancer drug that has been widely used in the
clinic. However, recently its application has been limited due to the cardiotoxic effects it has …

Background As an inflammation-related cytokine, interleukin (IL)-5 has been reported to be
involved in the development of cardiovascular diseases, such as chronic heart failure and …

The rate of ribosome biogenesis plays a vital role in cell cycle progression and proliferation
and is strongly connected with coronary restenosis and atherosclerosis. Blocking of …

The sympathetic system is involved in the arterial diseases, but its mechanism remains
poorly understood. The present study aimed to explore the impact of the sympathetic …

Renal interstitial fibrosis (RIF) is a common pathological hallmark of progressive chronic
kidney disease (CKD). Circular RNAs (circRNAs) are involved in certain renal diseases, but …

Background Partial bladder outlet obstruction (PBOO) promotes bladder detrusor
hyperplasia, increases bladder pressure, and decreases bladder compliance. To …

Intracellular Ca 2+ dysregulation is a key marker in septic cardiac dysfunction; however,
regulation of the classic Ca 2+ regulatory modules cannot successfully abolish this …