Leukocyte trafficking to the small intestine and colon

A Habtezion, LP Nguyen, H Hadeiba, EC Butcher - Gastroenterology, 2016 - Elsevier
Leukocyte trafficking to the small and large intestines is tightly controlled to maintain
intestinal immune homeostasis, mediate immune responses, and regulate inflammation. A …

Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations

ZS Wallace, H Mattoo, M Carruthers… - Annals of the …, 2015 - ard.bmj.com
Objectives We examined the utility of circulating total and IgG4+ plasmablasts as biomarkers
of diagnosis and disease activity in IgG4-related disease (IgG4-RD). Materials methods We …

B cells and antibodies in Kawasaki disease

ME Lindquist, MD Hicar - International Journal of Molecular Sciences, 2019 - mdpi.com
The etiology of Kawasaki disease (KD), the leading cause of acquired heart disease in
children, is currently unknown. Epidemiology supports a relationship of KD to an infectious …

Bacteroides vulgatus attenuates experimental mice colitis through modulating gut microbiota and immune responses

L Liu, M Xu, R Lan, D Hu, X Li, L Qiao, S Zhang… - Frontiers in …, 2022 - frontiersin.org
Introduction Bacteroides vulgatus is one of the predominant Bacteroides species in the
human gut and exerts a series of beneficial effects. The aim of this study was to investigate …

[HTML][HTML] Oral cholera vaccination promotes homing of IgA+ memory B cells to the large intestine and the respiratory tract

M Van Splunter, E Van Hoffen… - Mucosal …, 2018 - Elsevier
Oral cholera vaccination is used to induce immune responses in the intestines to protect
against cholera infection. However, oral vaccination may also affect immune responses in …

B-cell populations discriminate between pediatric-and adult-onset multiple sclerosis

A Schwarz, B Balint, M Korporal-Kuhnke… - Neurology …, 2016 - AAN Enterprises
Objective: To comparatively assess the B-cell composition in blood and CSF of patients with
pediatric-onset multiple sclerosis (pedMS) and adult-onset multiple sclerosis (adMS) …

[HTML][HTML] Trafficking receptor signatures define blood plasmablasts responding to tissue-specific immune challenge

Y Seong, NH Lazarus, L Sutherland, A Habtezion… - JCI insight, 2017 - ncbi.nlm.nih.gov
Antibody-secreting cells are generated in regional lymphoid tissues and traffic as
plasmablasts (PBs) via lymph and blood to target sites for local immunity. We used …

The shifted balance between circulating follicular regulatory T cells and follicular helper T cells in patients with ulcerative colitis

X Wang, Y Zhu, M Zhang, J Hou, H Wang… - Clinical …, 2017 - portlandpress.com
B-cell immunity participates in the pathogenesis of ulcerative colitis (UC). The immune
balance between follicular regulatory T (TFR) cells and follicular helper T (TFH) cells is …

Function and dysfunction of plasma cells in intestine

X Wang, G Hao, B Wang, C Gao, Y Wang, L Li, J Xu - Cell & Bioscience, 2019 - Springer
As the main player in humoral immunity, antibodies play indispensable roles in the body's
immune system. Plasma cells (PCs), as antibody factories, are important contributors to …

Antibodies and immunity during Kawasaki disease

MD Hicar - Frontiers in Cardiovascular Medicine, 2020 - frontiersin.org
The cause of Kawasaki disease (KD), the leading cause of acquired heart disease in
children, is currently unknown. Epidemiology studies support that an infectious disease is …