Cardiovascular disease and cancer: is there increasing overlap?

L Vincent, D Leedy, SC Masri, RK Cheng - Current oncology reports, 2019 - Springer
Abstract Purpose of Review Cancer and cardiovascular disease are the leading causes of
mortality in the USA. In this review, we highlight these shared disease pathways and provide …

[PDF][PDF] Ibrutinib-associated cardiotoxicity: from the pharmaceutical to the clinical

R Dong, Y Yan, X Zeng, N Lin, B Tan - Drug Design, Development …, 2023 - Taylor & Francis
Ibrutinib is the first-in-class Bruton tyrosine kinase (BTK) inhibitor that has revolutionized the
treatment of B cell malignancies. Unfortunately, increased incidences of cardiotoxicity have …

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights

PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …

Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence

IY Abdelgawad, KT Sadak, DW Lone… - Pharmacology & …, 2021 - Elsevier
Cancer treatment has been associated with accelerated aging that can lead to early-onset
health complications typically experienced by older populations. In particular, cancer …

Immune checkpoint inhibitor-related myocarditis

K Tajiri, K Aonuma, I Sekine - Japanese journal of clinical …, 2018 - academic.oup.com
Immune checkpoint inhibitors have demonstrated significant clinical benefit in many
cancers. The clinical benefit afforded by these treatments can be accompanied by a unique …

Cardio-oncology preventive care: racial and ethnic disparities

P Prasad, M Branch, D Asemota, R Elsayed… - Current Cardiovascular …, 2020 - Springer
Abstract Purpose of Review As cancer screening and treatment continue to improve, the
number of cancer survivors is growing rapidly. Cardiovascular disease is the leading cause …

CYP1B1 as a therapeutic target in cardio-oncology

AN Carrera, MKO Grant, BN Zordoky - Clinical Science, 2020 - portlandpress.com
Cardiovascular complications have been frequently reported in cancer patients and
survivors, mainly because of various cardiotoxic cancer treatments. Despite the known …

[HTML][HTML] Reverse Onco-Cardiology: What Is the Evidence for Breast Cancer? A Systematic Review of the Literature

I Boutas, A Kontogeorgi, SN Kalantaridou… - International Journal of …, 2023 - mdpi.com
Breast cancer and cardiovascular diseases (CVD) represent significant global health
challenges, with CVD being the leading cause of mortality and breast cancer, showing a …

[HTML][HTML] Oxytocin and cancer: An emerging link

B Lerman, T Harricharran… - World journal of clinical …, 2018 - ncbi.nlm.nih.gov
The neuropeptide hormone oxytocin, which is released from the posterior pituitary gland, is
involved in a number of physiological processes. Understanding of its effects is gradually …

[HTML][HTML] Leveraging the cardio-protective and anticancer properties of resveratrol in cardio-oncology

IY Abdelgawad, MKO Grant, BN Zordoky - Nutrients, 2019 - mdpi.com
Cardio-oncology is a clinical/scientific discipline which aims to prevent and/or treat
cardiovascular diseases in cancer patients. Although a large number of cancer treatments …