Parkinson's disease

BR Bloem, MS Okun, C Klein - The Lancet, 2021 - thelancet.com
Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

[HTML][HTML] The emerging evidence of the Parkinson pandemic

E Dorsey, T Sherer, MS Okun… - Journal of Parkinson's …, 2018 - content.iospress.com
Neurological disorders are now the leading source of disability globally, and the fastest
growing neurological disorder in the world is Parkinson disease. From 1990 to 2015, the …

[HTML][HTML] Global, regional, and national burden of Parkinson's disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

ER Dorsey, A Elbaz, E Nichols, N Abbasi… - The Lancet …, 2018 - thelancet.com
Background Neurological disorders are now the leading source of disability globally, and
ageing is increasing the burden of neurodegenerative disorders, including Parkinson's …

[HTML][HTML] Prevalence of Parkinson's disease across North America

C Marras, JC Beck, JH Bower, E Roberts, B Ritz… - NPJ Parkinson's …, 2018 - nature.com
Estimates of the prevalence of Parkinson's disease in North America have varied widely and
many estimates are based on small numbers of cases and from small regional …

[HTML][HTML] MPTP-induced mouse model of Parkinson's disease: A promising direction for therapeutic strategies

M Mustapha, CNM Taib - Bosnian journal of basic medical …, 2021 - ncbi.nlm.nih.gov
Among the popular animal models of Parkinson's disease (PD) commonly used in research
are those that employ neurotoxins, especially 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine …

[HTML][HTML] Corynoxine protects dopaminergic neurons through inducing autophagy and diminishing neuroinflammation in rotenone-induced animal models of …

L Chen, Y Huang, X Yu, J Lu, W Jia, J Song… - Frontiers in …, 2021 - frontiersin.org
Recent studies have shown that impairment of autophagy is related to the pathogenesis of
Parkinson's disease (PD), and small molecular autophagy enhancers are suggested to be …

Understanding the links between cardiovascular disease and Parkinson's disease

J Potashkin, X Huang, C Becker, H Chen… - Movement …, 2020 - Wiley Online Library
Studies investigating the associations between genetic or environmental factors and
Parkinson's disease (PD) have uncovered a number of factors shared with cardiovascular …

Projections of prevalence, lifetime risk, and life expectancy of Parkinson's disease (2010‐2030) in France

M Wanneveich, F Moisan… - Movement …, 2018 - Wiley Online Library
Background: Previous studies on the number of Parkinson's disease (PD) patients in the
future based on projections of population size underestimated PD burden because they did …

[HTML][HTML] A systematic review on the cognitive benefits and neurophysiological correlates of exergaming in healthy older adults

R Stojan, C Voelcker-Rehage - Journal of clinical medicine, 2019 - mdpi.com
Human aging is associated with structural and functional brain deteriorations and a
corresponding cognitive decline. Exergaming (ie, physically active video-gaming) has been …

[HTML][HTML] Burden of Parkinson Disease in China, 1990–2019: findings from the 2019 global burden of Disease Study

Z Zheng, Z Zhu, C Zhou, L Cao, G Zhao - Neuroepidemiology, 2023 - karger.com
Introduction: China has the most people with Parkinson disease (PD) in the world and is
estimated to have over half of the worldwide PD population. The objective of this study was …