Increased autophagy-related 5 gene expression is associated with collagen expression in the airways of refractory asthmatics
AH Poon, DF Choy, F Chouiali… - Frontiers in …, 2017 - frontiersin.org
Background Fibrosis, particularly excessive collagen deposition, presents a challenge for
treating asthmatic individuals. At present, no drugs can remove or reduce excessive …
treating asthmatic individuals. At present, no drugs can remove or reduce excessive …
Type V collagen-induced nasal tolerance prevents lung damage in an experimental model: new evidence of autoimmunity to collagen V in COPD
FSZ Robertoni, APP Velosa, LM Oliveira… - Frontiers in …, 2024 - frontiersin.org
Background Chronic obstructive pulmonary disease (COPD) has been linked to immune
responses to lung-associated self-antigens. Exposure to cigarette smoke (CS), the main …
responses to lung-associated self-antigens. Exposure to cigarette smoke (CS), the main …
Identification of autoantigens and their potential post-translational modification in EGPA and severe eosinophilic asthma
I Esposito, I Kontra, C Giacomassi… - Frontiers in …, 2023 - frontiersin.org
Background The chronic airway inflammation in severe eosinophilic asthma (SEA) suggests
potential autoimmune aetiology with unidentified autoantibodies analogous to …
potential autoimmune aetiology with unidentified autoantibodies analogous to …
Elastase alters contractility and promotes an inflammatory synthetic phenotype in airway smooth muscle tissues
AD Lockett, Y Wu, SJ Gunst - American Journal of …, 2018 - journals.physiology.org
Neutrophil elastase is secreted by inflammatory cells during airway inflammation and can
elicit airway hyperreactivity in vivo. Elastase can degrade multiple components of the …
elicit airway hyperreactivity in vivo. Elastase can degrade multiple components of the …
Collagen V oral administration decreases inflammation and remodeling of synovial membrane in experimental arthritis
SR Atayde, APP Velosa, S Catanozi, V Del Bianco… - Plos one, 2018 - journals.plos.org
Because collagen type V (Col V) can be exposed in tissue injury, we hypothesized that oral
administration of this collagen species modulates the inflammation and remodeling of …
administration of this collagen species modulates the inflammation and remodeling of …
Intranasal administration of type V collagen reduces lung carcinogenesis through increasing endothelial and epithelial apoptosis in a urethane-induced lung tumor …
ER Parra, RA Alveno, CB Faustino… - Archivum immunologiae …, 2016 - Springer
Abstract Type V collagen (Col V) is a “minor” component of normal lung extracellular matrix,
which is subjected to decreased and abnormal synthesis in human lung infiltrating …
which is subjected to decreased and abnormal synthesis in human lung infiltrating …
[HTML][HTML] Estudo do remodelamento cutâneo durante o desenvolvimento do modelo de esclerose sistêmica induzido com colágeno V
ZAJ Queiroz - 2024 - bdtd.ibict.br
A esclerose sistêmica (ES) é uma doença crônica do tecido conjuntivo caracterizada por
vasculopatia proliferativa, reatividade imunológica e fibrose da pele e órgãos internos. A …
vasculopatia proliferativa, reatividade imunológica e fibrose da pele e órgãos internos. A …
Estudo dos efeitos da instilação nasal de colágeno tipo V na inflamação e remodelamento pulmonar na DPOC experimental
FSZ Robertoni - 2023 - teses.usp.br
O tabagismo, principal causa da doença pulmonar obstrutiva crônica (DPOC), induz uma
inflamação pulmonar persistente, que resulta na degradação da matriz extracelular (MEC) …
inflamação pulmonar persistente, que resulta na degradação da matriz extracelular (MEC) …