Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation

L Core, K Adelman - Genes & development, 2019 - genesdev.cshlp.org
Precise spatio–temporal control of gene activity is essential for organismal development,
growth, and survival in a changing environment. Decisive steps in gene regulation involve …

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia

L Lao, I Bourdeau, L Gagliardi, X He, W Shi… - Nucleic acids …, 2022 - academic.oup.com
ARMC5 is implicated in several pathological conditions, but its function remains unknown.
We have previously identified CUL3 and RPB1 (the largest subunit of RNA polymerase II …

Transcriptional Shift and Metabolic Adaptations during Leishmania Quiescence Using Stationary Phase and Drug Pressure as Models

M Jara, M Barrett, I Maes, C Regnault, H Imamura… - Microorganisms, 2022 - mdpi.com
Microorganisms can adopt a quiescent physiological condition which acts as a survival
strategy under unfavorable conditions. Quiescent cells are characterized by slow or non …

New ex vivo models to study the mechanical interplay between muscle cells and their microenvironment

N Rose - 2021 - theses.hal.science
Ex vivo systems are under increasing interest for bioethical, legal and financial stakes. To
study muscle function and regeneration, medical research requires functional analysis …