Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …
community. Larvae of Galleria mellonella are a widely used model for studying …
Aspergillus fumigatus and aspergillosis: From basics to clinics
The airborne fungus Aspergillus fumigatus poses a serious health threat to humans by
causing numerous invasive infections and a notable mortality in humans, especially in …
causing numerous invasive infections and a notable mortality in humans, especially in …
[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms
P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …
diseases in humans, invasive fungal infections carry high morbidity and mortality …
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
The cytochrome P450 enzyme lanosterol 14α-demethylase (LDM) is the target of the azole
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
Action mechanisms of probiotics on Candida spp. and candidiasis prevention: an update
Due to the high incidence of fungal infections caused by Candida species and their
increasing resistance to antimicrobial treatments, alternative therapies such as probiotics …
increasing resistance to antimicrobial treatments, alternative therapies such as probiotics …
Standardization of G. mellonella Larvae to Provide Reliable and Reproducible Results in the Study of Fungal Pathogens
In the past decade, Galleria mellonella (wax moth) larvae have become widely used as a
non-mammalian infection model. However, the full potential of this infection model has yet to …
non-mammalian infection model. However, the full potential of this infection model has yet to …
A powerful in vivo alternative model in scientific research: Galleria mellonella
P Singkum, S Suwanmanee, P Pumeesat… - Acta microbiologica et …, 2019 - akjournals.com
Murine models are suggested as the gold standard for scientific research, but they have
many limitations of ethical and logistical concern. Then, the alternative host models have …
many limitations of ethical and logistical concern. Then, the alternative host models have …
Microbiology's next top model: Galleria in the molecular age
Galleria mellonella has risen to fame as an invertebrate model organism given its ethical
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …
advantages, low maintenance costs, rapid reproduction time, short life cycle, high number of …
Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its close relatives
Fungal diseases affect millions of humans annually, yet fungal pathogens remain
understudied. The mold Aspergillus flavus can cause both aspergillosis and fungal keratitis …
understudied. The mold Aspergillus flavus can cause both aspergillosis and fungal keratitis …
Virulence of Clinical Candida Isolates
M Mroczyńska, A Brillowska-Dąbrowska - Pathogens, 2021 - mdpi.com
The factors enabling Candida spp. infections are secretion of hydrolytic enzymes,
adherence to surfaces, biofilm formation or morphological transition, and fitness attributes …
adherence to surfaces, biofilm formation or morphological transition, and fitness attributes …