Migraine is a disabling primary headache disorder that directly affects more than one billion
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …

Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

The understanding of migraine pathophysiology is advancing rapidly. Improved
characterisation and diagnosis of its clinical features have led to the view of migraine as a …

Migraine is a common, disabling neurological disorder characterized by multiple phases:
premonitory, aura, headache, postdrome, and interictal. Our understanding of the …

Migraine is a common, multifactorial, disabling, recurrent, hereditary neurovascular
headache disorder. It usually strikes sufferers a few times per year in childhood and then …

Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed
by suppression of brain activity, is a remarkably complex event that involves dramatic …

Functioning of the glymphatic system, a network of paravascular tunnels through which
cortical interstitial solutes are cleared from the brain, has recently been linked to sleep and …

There are many options for acute migraine attack treatment, but none is ideal for all patients.
This study aims to review current medical office‐based acute migraine therapy in adults and …

A migraine attack is an extraordinarily complex brain event that takes place over hours to
days. This review focuses on recent human studies that shed light on the evolution of a …