[HTML][HTML] Neurosteroids as regulators of neuroinflammation

C Yilmaz, K Karali, G Fodelianaki, A Gravanis… - Frontiers in …, 2019 - Elsevier
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …

Contributions of sex to cerebrovascular function and pathology

LS Robison, OJ Gannon, AE Salinero, KL Zuloaga - Brain research, 2019 - Elsevier
Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …

Progesterone for acute traumatic brain injury

J Ma, S Huang, S Qin, C You… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Traumatic brain injury (TBI) is a leading cause of death and disability, and the
identification of effective, inexpensive and widely practicable treatments for brain injury is of …

Neuroprotective effects of estrogen in CNS injuries: insights from animal models

N Raghava, BC Das, SK Ray - Neuroscience and neuroeconomics, 2017 - Taylor & Francis
Among the estrogens that are biosynthesized in the human body, 17β-estradiol (estradiol or
E2) is the most common and the best estrogen for neuroprotection in animal models of the …

Clinical relevance of midline fluid percussion brain injury: acute deficits, chronic morbidities and the utility of biomarkers

J Lifshitz, RK Rowe, DR Griffiths, MN Evilsizor… - Brain injury, 2016 - Taylor & Francis
Background: After 30 years of characterisation and implementation, fluid percussion injury
(FPI) is firmly recognised as one of the best-characterised reproducible and clinically …

Aquaporin 4 in traumatic brain injury: from molecular pathways to therapeutic target

E Dadgostar, S Rahimi, S Nikmanzar, S Nazemi… - Neurochemical …, 2022 - Springer
Traumatic brain injury (TBI) is known as an acute degenerative pathology of the central
nervous system, and has been shown to increase brain aquaporin 4 (AQP4) expression …

Effects of female sex steroids administration on pathophysiologic mechanisms in traumatic brain injury

M Khaksari, Z Soltani, N Shahrokhi - Translational stroke research, 2018 - Springer
Secondary brain damage following initial brain damage in traumatic brain injury (TBI) is a
major cause of adverse outcomes. There are many gaps in TBI research and a lack of …

Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury

A Sunny, RR James, SR Menon, S Rayaroth… - Neurochemistry …, 2023 - Elsevier
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality among
young adults and the elderly. In the United States, TBI is responsible for around 30 percent …

Possible involvement of female sex steroid hormones in intracellular signal transduction mediated by cytokines following traumatic brain injury

F Farahani, M Khaksari, S Amiresmaili, M Iranpour… - Brain research …, 2022 - Elsevier
Introduction The aim of this study was to determine the anti-inflammatory effect of female sex
hormones on the level of intracellular molecules of cytokine signaling pathway after diffuse …

The changes of brain edema and neurological outcome, and the probable mechanisms in diffuse traumatic brain injury induced in rats with the history of exercise

N Soltani, Z Soltani, M Khaksari, G Ebrahimi… - Cellular and molecular …, 2020 - Springer
Since no definitive treatment has been suggested for diffuse traumatic brain injury (TBI), and
also as the effect of exercise has been proven to be beneficial in neurodegenerative …