Mast cells have existed long before the development of adaptive immunity, although they
have been given different names. Thus, in the marine urochordate Styela plicata, they have …

Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Mast cells are (in) famous for their role in allergic diseases, but the physiological and
pathophysiological roles of this ingenious cell are still not fully understood. Mast cells are …

There is clear evidence that exposure to environmental air pollution is associated with
immune dysregulation, asthma, and other allergic diseases. However, the burden of air …

The existence of the neural control of mast cell functions has long been proposed. Mast cells
(MCs) are localized in association with the peripheral nervous system (PNS) and the brain …

Background Airway hyperresponsiveness (AHR) is a feature of asthma in which airways are
hyperreactive to stimuli causing extensive airway narrowing. Methacholine provocations …

Whatever the exposure route, chemical, physical and biological pollutants modify the whole
organism response, leading to nerve, cardiac, respiratory, reproductive, and skin system …

Allergic asthma is a common chronic inflammation of the airways and causes airway
remodeling eventually. For a long time, investigators have been focusing on the …

People spend one third of their life sleeping, but the bedroom, as a specific micro-
environment, is often neglected when assessing human exposure to air pollutants. However …

Abstract Purpose of Review The recent increase in childhood food allergy prevalence
strongly suggests that environmental exposures are contributing to food allergy …